Biomedical subjects

Norberto Sotelo-Cruz

Publications and source records attributed to Norberto Sotelo-Cruz.

3 recordsLinked to original sources

PubMedDate not supplied

[Treatment of iron deficiency in preschool children with a weekly dose of ferrous sulfate].

INTRODUCTION: Iron deficiency is the most frequent haematological disease during the paediatric age and is a health public problem; the iron deficiency has a special interest during early development of human beings; in recent years the group of research recommend intermittent treatment, with ferrous sulphate every week because is more easily adhesion to treatment. OBJECTIVE: To know iron concentration in plasma after treatment, given oral ferrous sulphate daily and single dose every week. METHODS AND MATERIAL: We established two groups A and B, with ten iron deficiency pre-school children each one. RESULTS: Group A: the children received oral ferrous sulphate twice a day during three months; the doses were 3.5 mg of ferric iron per kilogram of weight in children with ages less of three years old, and 2.5 mg/kg/day in children with three to five years old. After the treatment all the patients improved haemoglobin, ferritin an iron concentrations (p = 0.001). Group B: The patient received the some dose per kilogram of weight like that of group A, in a single dose weekly for three months, there was an improvement in haemoglobin not reaching normal levels, half of the patients improved iron and ferritin observing statistical significance; haemoglobin (p = 0.001) iron (p = 0.062) and ferritin (p = 0.01). CONCLUSION: The administration of ferrous sulphate daily provide an positive balance of iron status for the group A. Group B: that they received iron weekly dose showed changes to positive balance of iron status with a statistical significance, it is probably that the half doses of ferrous sulphate also improve the anaemia by iron deficiency.

Age Factors↗

PubMedDate not supplied

[Rattlesnake bite poisoning, health damage and treatment in children].

INTRODUCTION: In Mexico, we do not know the exact number of cases and the magnitude of health damage conditioned by poisonous rattlesnake bites, and little relative information exists in pediatric population. OBJECTIVE: To inform on continued follow-up of 55 patients at a children's hospital, and to propose a therapeutic sequence adequate for children. MATERIALS AND METHODS: We reviewed clinical records and variables were origin, age, sex, time of year, previous care measures, time passed, hospital treatment complications and care cost. RESULTS: Rattlesnake bite occurred around the home at times and at times inside the home in rural areas; we did not observe any noticeable difference in gender; snake variety most involved was Crotalus atrox, anatomic site most injured were the lower extremities in 78%. Prior to admission, 50% received insufficient antivenom serum doses; the most frequent complication was hematologic in 69%. One patient died with multiple organ failure and disseminated intravascular coagulation (DIC). The treatment protocol that we have recommended since 1986 at the Hospital Infantil del Estado de Sonora, revised and modified in 1996, reduced hospital stay from 15 to 5 days. CONCLUSION: The protocol used avoided further complications and had a favorable influence on cost reduction.

Adolescent↗

PubMedDate not supplied

[Persistent hyperinsulinemic hypoglycemia. Two case reports].

We report two cases of infants who presented seizures and persistent hypoglycemia. In both infants, we established diagnosis of persistent hypoglycemia by hyperinsulinism (PHH); glycemic/insulinic ratio was > 0.3, and we found no pancreatic changes by means of other diagnostic procedures. The medical treatment consisted of hydrocortisone, diazoxide, and octreotide without response. Definitive treatment made was sub-total pancreatectomy; postoperatory evolution was satisfactory, and the histologic report showed changes in Langerhans islet of nesidioblastosis. We conclude that PHH and glucose/insulin ratio > 0.3 indicates that surgical treatment with pancreatectomy should not be delayed.

Female↗