When does a random flap die?

S P Campbell; M L Moss; N E Hugo

doi:10.1097/00006534-199204000-00023

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PubMed · 1546086

When does a random flap die?

S P Campbell·M L Moss·N E Hugo

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Abstract

A random flap can be constructed, its circulation determined, and the ischemic portion identified. Left untreated for a period, the critical ischemia time, the ischemic portion will die and is clinically recognized several days later. What is not known is when this tissue, destined to die, actually dies. To ascertain this time, we compared the percent necrosis of a distal 3 x 3 cm segment of a 10 x 3 cm reverse McFarlane random flap with a known distribution of necrosis to the percent necrosis of the distal 3 x 3 cm of full-thickness skin grafts taken from a similar reverse McFarlane flap at 0, 4, 8, 12, and 16 hours after pedicle construction. Implicit in this experiment is the assumption that necrosis of the full-thickness skin grafts in excess of that of control animals represented skin no longer viable. Sometime between 8 and 12 hours, the percent necrosis of the full-thickness skin grafts surpassed that of the control, and it was concluded that this graft was dead prior to grafting. Thus it is suggested that critical ischemia time and death of the flap tissue are nearly identical, and the latter occurs at between 8 and 12 hours.

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Animals Male Necrosis Rats Rats, Inbred Strains Skin Surgical Flaps Time Factors Journal Article

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S P Campbell, M L Moss, N E Hugo. 1992. When does a random flap die?. https://doi.org/10.1097/00006534-199204000-00023

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