PubMed · 1545635
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F A Navarro, J A López-Gil. 1992-01-18. [Randomization, informed consent and double-blind].. https://pubmed.ncbi.nlm.nih.gov/1545635/
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Here we show, in a double-blind, randomized, placebo-controlled trial in 37,107 fully immunized infants in Soweto, South Africa, that a 9-valent pneumococcal conjugate vaccine, PncCV, prevents 31% (95% confidence interval = 15-43%) of pneumonias associated with any of seven respiratory viruses in children in hospital. These data suggest that the pneumococcus has a major role in the development of pneumonia associated with these viruses and that viruses contribute to the pathogenesis of bacterial pneumonia.
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