PubMed · 14798443
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M ALBEAUX-FERNET, L BELLOT. 1950-11-18. [Cryptomenopause].. https://pubmed.ncbi.nlm.nih.gov/14798443/
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We investigated the effect of the anti-progestogen mifepristone (RU-486) on climacteric complaints. Four hysterectomized postmenopausal women, with at least 35 hot flushes per week, were treated with daily 200mg RU-486 for 6 weeks. RU-486 did not significantly improve climacteric complaints. Although this result does not support further clinical research with this dose of RU-486 for the treatment of climacteric complaints, potential effects of higher, but more interestingly of lower, dosages of RU-486 cannot be excluded.
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