G proteins.

J R Hepler; A G Gilman

doi:10.1016/0968-0004(92)90005-t

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G proteins.

J R Hepler·A G Gilman

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Abstract

The family of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) serves an essential role in transducing receptor-generated signals across the plasma membrane. Recent findings reveal unexpected functional roles for individual G protein subunits. Thus, GTP-binding alpha-subunits and the beta gamma-subunit complex can influence the activity of effector molecules independently or simultaneously, either synergistically or in opposition, to elicit a complex constellation of cellular events.

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Animals Cell Membrane GTP-Binding Proteins Humans Signal Transduction Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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J R Hepler, A G Gilman. 1992. G proteins.. https://doi.org/10.1016/0968-0004(92)90005-t

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