Nuclear and unclear functions of SUMO.

Jacob-S Seeler; Anne Dejean

doi:10.1038/nrm1200

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Nuclear and unclear functions of SUMO.

Jacob-S Seeler·Anne Dejean

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Abstract

Post-translational modification by the ubiquitin-like SUMO protein is emerging as a defining feature of eukaryotic cells. Sumoylation has crucial roles in the regulatory challenges that face nucleate cells, including the control of nucleocytoplasmic signalling and transport and the faithful replication of a large and complex genome, as well as the regulation of gene expression.

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Animals Cell Nucleus Humans SUMO-1 Protein Transcription, Genetic Journal Article Research Support, Non-U.S. Gov't Review

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Jacob-S Seeler, Anne Dejean. 2003. Nuclear and unclear functions of SUMO.. https://doi.org/10.1038/nrm1200

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