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PubMed · 12791246

Complementing thymidylate synthase.

William R Montfort
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Abstract

The structure of thymidylate synthase complementing protein with substrates dUMP and FAD, presented in this issue of Structure, sheds light on a fascinating new catalytic mechanism, suggests a strategy for the design of new antimicrobial compounds, and highlights the promise of proteomics in medicine.

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Deoxyuracil NucleotidesDrug DesignFlavin-Adenine DinucleotideHumansMolecular StructureThymidylate SynthaseCommentNews

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William R Montfort. 2003. Complementing thymidylate synthase.. https://doi.org/10.1016/s0969-2126(03)00101-1

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