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PubMed · 12480342

Knockdown stands up.

P Mathijs Voorhoeve·Reuven Agami
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Abstract

In the past year, the genetic research of mammalian cells in vitro has gained the advantages of RNA interference (RNAi), a process found in worms and plants by which double stranded RNAs mediate selective gene inactivation through mRNA destruction. Recently, two papers have shown that genes could be suppressed in vivo in mammals by RNAi, which has potential implications for both therapeutics and research.

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AnimalsGene SilencingGenetic TechniquesHumansMiceMice, KnockoutRNA InterferenceJournal ArticleReview

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P Mathijs Voorhoeve, Reuven Agami. 2003. Knockdown stands up.. https://doi.org/10.1016/s0167-7799(02)00002-1

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