Somatic cell nuclear transfer.

I Wilmut; N Beaujean; P A de Sousa; A Dinnyes; T J King; L A Paterson; D N Wells; L E Young

doi:10.1038/nature01079

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Somatic cell nuclear transfer.

I Wilmut·N Beaujean·P A de Sousa·A Dinnyes·T J King·L A Paterson·D N Wells·L E Young

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Abstract

Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.

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Animals Cattle Cell Cycle Cell Differentiation Cloning, Organism Embryonic and Fetal Development Fetal Death Forecasting Gene Expression Regulation, Developmental Goats Mice Nuclear Transfer Techniques Oocytes Ploidies Sheep Swine Journal Article Research Support, Non-U.S. Gov't

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I Wilmut, N Beaujean, P A de Sousa, A Dinnyes, T J King, L A Paterson, D N Wells, L E Young. 2002-10-10. Somatic cell nuclear transfer.. https://doi.org/10.1038/nature01079

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