Morphogen gradient interpretation.

J B Gurdon; P Y Bourillot

doi:10.1038/35101500

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Morphogen gradient interpretation.

J B Gurdon·P Y Bourillot

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Abstract

A morphogen gradient is an important concept in developmental biology, because it describes a mechanism by which the emission of a signal from one part of an embryo can determine the location, differentiation and fate of many surrounding cells. The value of this idea has been clear for over half a century, but only recently have experimental systems and methods of analysis progressed to the point where we begin to understand how a cell can sense and respond to tiny changes in minute concentrations of extracellular signalling factors.

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Animals Cell Differentiation Chemotactic Factors Drosophila Embryonic Induction Gene Expression Regulation, Developmental Morphogenesis Signal Transduction Wings, Animal Journal Article Research Support, Non-U.S. Gov't Review

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J B Gurdon, P Y Bourillot. 2001-10-25. Morphogen gradient interpretation.. https://doi.org/10.1038/35101500

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