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PubMed · 11661045

Ethically questionable data: publish or reject?

Lois DeBakey
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AttitudeBiomedical ResearchDecision MakingEditorial PoliciesEthics CommitteesEthics Committees, ResearchHuman ExperimentationPublic OpinionPublishingReference StandardsResearchSocial ChangeSocial ResponsibilityJournal Article

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Lois DeBakey. 1974. Ethically questionable data: publish or reject?. https://pubmed.ncbi.nlm.nih.gov/11661045/

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Drops in estrogen levels affect brain, body and behavior: reported relationship between attitudes and menopausal symptoms.

Bloch found that women who had more menopausal symptoms had a more negative view of menopause than women who had fewer symptoms. Bloch's conclusion that a negative view of menopause will lead to more symptoms implies a cause and effect assumption that is not warranted and is also counter-intuitive. Current research on the neural effects of estrogen suggest that the observed relationship is more likely to be due to the fact that some women experience negative symptoms during menopause as a result of diminished levels of estrogen. This, in turn leads these same women to adopt a more negative view of menopause, at least compared with women who have relatively less severe symptoms.

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