PubMed · 11540682
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R R Burton, L J Meeker. 1997. Taking gravity into space.. https://pubmed.ncbi.nlm.nih.gov/11540682/
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The risk of venal thrombosis and pulmonary embolia during aviation is rather small. The risk markedly rises during long flights (over 7500 km) and namely in elderly persons. Danger of the disease can be lowered by lower limbs exercising, liberal intake of soft drinks, and by elastic calf bandages. Persons of the high risk are candidates for low-molecular heparin administration.
The increasing use of air travel suggests the need for risk assessment and cytogenetic analysis of flight personnel, to check for the risk of developing cancer. Taking into consideration occupational risk and possible confounding factors, we used traditional cytogenetics, the micronucleus test and fluorescent in situ hybridization (FISH) analysis to study 48 male crew members working on long-haul flights and a control group of 48 ground staff. Compared to controls, we detected a significant increase in the relative risk of gaps and breaks (adjusted odds ratio (OR(adj))--7.8; 95% confidence interval (CI) - 2.4-24.9) and of translocations (OR(adj)--5.1; 95% CI 1.5-17.3) in crew members, with a non-significant difference in the other chromosomal aberrations. The possibility of a correlation between translocations and cancer risk highlights the need for preventive measures for aircraft personnel.