Leptin-induced decrease in food intake in chickens.

D M Denbow; S Meade; A Robertson; J P McMurtry; M Richards; C Ashwell

doi:10.1016/s0031-9384(99)00258-9

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Leptin-induced decrease in food intake in chickens.

D M Denbow·S Meade·A Robertson·J P McMurtry·M Richards·C Ashwell

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Abstract

The effect of intracerebroventricular (i.c.v.) injection of leptin was investigated using broiler and Single Comb White Leghorn (SCWL)-type chickens. These represent relatively fast- and slow-growing birds, respectively. The i.c.v. injection of leptin decreased food intake in both broilers and Leghorns in a dose-dependent manner. The most efficacious dose appeared to be 10 microg in both types of chickens. Water intake was generally not affected by leptin, indicating that this effect was not due to general malaise. It appears that leptin can act within the central nervous sytstem of birds to decrease food intake.

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Aging Animals Chickens Depression, Chemical Drinking Eating Growth Humans Injections, Intraventricular Leptin Male Recombinant Proteins Journal Article

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D M Denbow, S Meade, A Robertson, J P McMurtry, M Richards, C Ashwell. 2000. Leptin-induced decrease in food intake in chickens.. https://doi.org/10.1016/s0031-9384(99)00258-9

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