PubMed · 10636310
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P J Baskett, P A Steen. 1999. Interventions on the recently dead.. https://doi.org/10.1016/s0300-9572(99)00108-2
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The transmission of infection by a cadaver donor organ can result not only in loss of the allograft but also in death of the immunosuppressed recipient. Despite the shortage of cadaver organ donors, every donor must be evaluated thoroughly for the potential transmission of infectious disease, because the consequences of the organ donor events can have a profound effect on the transplant outcome. This review summarizes current knowledge about serological screening of organ donors to determine the suitability of organs from cadaver donors for transplantation.
A nationwide survey and recent information documented 57 patients with Creutzfeldt-Jakob disease (CJD) who had received dura mater grafts during the period between January 1979 and September 1999. At least 54 of these 57 patients received the same brand of dura mater graft from the same processor. Mean age at disease onset in the 57 patients with dural grafts was younger (51.9 years) than that in patients with sporadic CJD (63 years) (p < 0. 0001). Initial symptoms were cerebellar ataxia, disorientation, and visual or oculomotor disturbance.
Here at the "Body Farm," a research plot where human corpses are studied as they decompose, the corpses are teaching scientists much about how to reconstruct the manner and circumstances of unexplained deaths. In fact, new techniques developed at the site, officially known as the University of Tennessee, Knoxville's, Anthropological Research Facility, are already beginning to land criminals behind bars.