PubMed · 10570407
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
S R Cole, R C Blair. 1999. Overlapping confidence intervals.. https://doi.org/10.1016/s0190-9622(99)70281-1
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
Explore the source record for details and available documents.
Receiver operator characteristic (ROC) curves are recommended to assess the diagnostic value of tests depending on a single cut-off value of a continuous variable. These ROC curves show the true-positive rate (sensitivity) against the false-positive rate (1-specificity). It is desirable, especially in situations with small samples of observations, to display confidence bounds of the ROC curve. This paper presents a Perl program which calculates the ROC curve and its distribution-free confidence bounds. A simple user interface also written in Perl permits their display.
A common task in microbiology involves determining the composition of a mixed population of individuals by drawing a sample from the population and using some procedure to identify the individuals in the sample. There may be a significant probability that the identification procedure misidentifies some members of the sample (for example, because the available data are insufficient unambiguously to identify an individual) which makes finding the proportions in the underlying population non-trivial. A further complication arises where individuals are present in the population that do not belong to any of the subpopulations recognised by use of the identification procedure. A simple algorithm is presented to address these problems and construct a maximum likelihood estimate of the proportions, together with confidence limits. The technique is illustrated using an example drawn from flow cytometry in which phytoplankton cells are identified from flow cytometry data by an RBF neural network, and the limitations of the approach are discussed.