hnRNP complexes: composition, structure, and function.

A M Krecic; M S Swanson

doi:10.1016/s0955-0674(99)80051-9

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hnRNP complexes: composition, structure, and function.

A M Krecic·M S Swanson

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Abstract

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are predominantly nuclear RNA-binding proteins that form complexes with RNA polymerase II transcripts. These proteins function in a staggering array of cellular activities, ranging from transcription and pre-mRNA processing in the nucleus to cytoplasmic mRNA translation and turnover. Recent studies suggest that several fundamental characteristics of hnRNPs account for their involvement in multiple regulatory pathways.

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Animals Base Sequence Heterogeneous-Nuclear Ribonucleoproteins Humans RNA Precursors RNA Processing, Post-Transcriptional RNA, Messenger RNA-Binding Proteins Ribonucleoproteins Transcription, Genetic Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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A M Krecic, M S Swanson. 1999. hnRNP complexes: composition, structure, and function.. https://doi.org/10.1016/s0955-0674(99)80051-9

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