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PubMed · 1028629

Developing optimum drug regimens.

M S Carey·R W Noyes·S A Pasquale·J J Frey·J S Lawson
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Abstract

In clinical pharmacological trials the determination of the optimum regimen for a drug using the technique of response surface analysis is proposed as being more advantageous than traditional analyses of dose response relationships. Major considerations in favour of this technique are that the optimum regimem can be identified with a minimum of human experimentation, and unacceptable regimens are eliminated from the study early, at a substantial saving of time and money.

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M S Carey, R W Noyes, S A Pasquale, J J Frey, J S Lawson. 1976. Developing optimum drug regimens.. https://doi.org/10.1177/030006057600400501

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