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Biomedical subjects

Z Shapira

Publications and source records attributed to Z Shapira.

At least 91 records · Page 5Linked to original sources
PubMed1988

Page kidney phenomenon in kidney allograft following peritransplant lymphocele.

A case of kidney allograft dysfunction in a recipient with a prior lymphocele is described. We attribute it to a Page kidney phenomenon caused by a constrictive pericapsular fibrosis. Surgical exploration and excision of the fibrotic tissue were followed by the recovery of renal transplant function. To our knowledge, only 1 case of Page kidney in renal allograft due to peritransplant hematoma has been described in the literature.

Adult↗
PubMed1986

Kidney-derived urinary antigens assayed with monoclonal antibodies for the detection of renal damage.

For the quantitation of kidney-derived Urinary Antigens (UA) monoclonal antibodies specific for antigens localized in cells of defined subunits of the nephron were applied in sandwich ELISA. Antigen excretion was measured in the urine of healthy individuals, patients suffering from various diseases, kidney transplant recipients, and healthy volunteers receiving therapeutic doses of antibiotic drugs. In healthy individuals, in patients with diseases primarily affecting the glomerulus, and in inactive phases of chronic diseases antigen excretion was low. Toxic drug effects enhanced antigenuria. Excretion of some or all of the antigens always indicated tubular alterations. The tests thus provide information on location and extent of acute primary tubular damage.

Antibodies, Monoclonal↗
PubMed1985

Scintigraphic detection of vascular and urological complications in the transplanted kidney: 133 cases.

A total of 133 consecutive kidneys, grafted during the past 2 years, were followed by scintigraphy. Patterns of prerenal, renal, and postrenal complications were recognized. Vascular thrombosis diagnosed by photodeficiency of the transplanted kidney was diagnosed and confirmed in 10 patients. Fourteen patients having postrenal urological complications (12 leaks and 2 ureteral obstructions) were all recognized in the late phase of the scintigraphic study. The differentiation between the known parenchymatous causes of anuria was less satisfactory. As a whole, all cases were recognized in which the complication was due to causes that required surgical intervention.

Hematoma↗
PubMed1985

The use of the portal system for the transplantation of a neonate kidney graft in a child with Wilms' tumor.

A single an-encephalus neonate kidney graft was transplanted into the portal system of a 6-year-old recipient who had previously undergone removal of the right kidney and inferior vena cava because of Wilms tumor. The left kidney ceased to function shortly thereafter. The child was supported very poorly on hemodialysis, and showed repeated very high levels of cytotoxic antibodies in her serum. The first cross-negative kidney graft that was available harbored two main arteries and duplicate collecting system with two very thin ureters. These vascular anatomic and pathologic variations of both donor graft and recipient necessitated the use of the portal system for renal graft venous drainage and the aorta for the graft revascularization. The ureters that had pinpoint-like lumen were inserted together into the lumen of the native ureter stump and fixated. One year after the transplantation the serum creatinine level is 1.8 mg/dL.

Aorta↗
PubMed1985

Infections in renal transplant recipients in Israel.

A 5-year retrospective survey of infections following 258 renal transplants in 233 patients is reported from a large medical center in Israel. The most common sites of infection were the urinary tract, the surgical incision, and the lung. We recorded 157 episodes of bacteriuria, 75% during the first month following transplantation. In 24 patients, 25 episodes of bacteremia were documented, with gram-negative bacteria being the most commonly involved organism. Pneumonia was diagnosed in 36 patients and was associated with relatively high mortality. Cytomegalovirus was the most common single organism responsible for infection. Fatal rhinocerebral mucormycosis was observed in three patients and was the most common invasive fungal infection. Other serious opportunistic infections were seen only rarely. Infectious diseases were the most frequent cause of death (51.1%) among these patients.

Adolescent↗