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Biomedical subjects

Z Liu

Publications and source records attributed to Z Liu.

At least 1,369 records · Page 76Linked to original sources
PubMed1990

[A case-control study of lung cancer risk factors in Xuanwei].

In Xuanwei County, Yunnan Province, lung cancer mortality is the highest in China. The former studies showed that indoor burning of "smokey" coal was an important cause for high incidence of Xuanwei lung cancer. The 1:Mi matched case-control study was undertaken to examine the association with other risk factors such as smoking. 110 cases of primary lung cancer newly diagnosed and 426 controls individually matched were interviewed. Conditional logistic regression was employed to examine the effect modification and to control confounding. The analytic results showed that smoking was one of the risk factors of Xuanwei male lung cancer. No relation was found between passive smoking and female lung cancer. The association was observed for familial history of lung cancer.

Case-Control Studies↗
PubMed1990

[Clinical aspects and immunology of facial neuritis].

A clinical and immunological study was carried out in 75 patients with facial neuritis. It was found that the concentration of serum IgG and IgA were increased. The frequency of CIC in blood was higher than normal. In comparison with the controls, the difference was statistically significant (P less than 0.01). However, IgM, Ch50 and C3 levels were not deviated from normals. It was suggested that immune functions of patients with facial neuritis were abnormal. The data presented might set a clue in exploring the pathogenesis of this disease. Of these 75 cases, 2 were bilateral simultaneous Bell's palsy, 11 unilateral recurrent and bilateral alternating Bell's palsy. They might be considered as special types of Bell's palsy.

Adult↗
PubMed1990

[Glucocorticoid receptors on human peripheral mononuclear and polymorphonuclear leucocytes: changes in patients with yang-deficiency].

It was found that, in former works, the glucocorticoid receptors (GCR) on peripheral mixed leucocytes in patients with Yang-deficiency were decreased. In this work, the mixed leucocytes were further separated into mononuclear (MNL) and polymorphonuclear (PML) leucocytes, and GCR were determined in each part of leucocytes. GCR on MNL and PML in 6 Yang deficient patients were 3473 +/- 413 and 4433 +/- 651 sites/cell respectively, statistically significant from the normal control group (4462 +/- 962 and 5622 +/- 782 sites/cell respectively, P less than 0.05). GCR on MNL, PML and mixed leucocytes in 5 patients were determined simultaneously, and all lowered from the control group. The results were 3369 +/- 370, 4986 +/- 419 and 4524 +/- 852 sites/cell respectively, with the lowest GCR on MNL and highest on PML.

Adult↗
PubMed1989

Environmental factors and Parkinson's disease: a case-control study in China.

We studied the role of environment in the development of Parkinson's disease (PD) in China, where industrialization is relatively recent and the population geographically stable. Using a case-control method, we investigated the relationship between PD and exposure to the following factors before disease onset: place of residence, source of drinking water, environmental and occupational exposure to various agricultural and industrial processes. Occupational or residential exposure to industrial chemicals, printing plants, or quarries was associated with an increased risk of developing PD. In contrast, living in villages and exposure to the common accompaniments of village life, wheat growing and pig raising, were associated with a decreased risk for PD. PD cases and controls did not differ with respect to other factors investigated. These findings are consistent with the hypothesis that environmental exposure to certain industrial chemicals may be related to the development of PD.

Adult↗
PubMed1989

Urban-rural and educational differentials in marital status in China.

Since 1950, laws aimed at delaying marriage have been 1 of the major means of slowing population growth in China, where marriage is nearly universal. Age at marriage has risen in recent decades, but not to the same extent in all localities. This article uses cross-tabulated data from China's 1982 census to assess the effects of urban-rural residence and educational level on the ages at which men and women have been marrying. The data also reveal the effects of residence and education on widowhood, divorce, and current marital status. As expected, exposure to development, indicated by urban residence and higher education, is associated with later marriage, but it also increases the likelihood of ever marrying, especially for men. Women's tendency to seek social mobility by marrying men from economically more developed areas results in bachelorhood for a substantial percentage of rural men, especially those who are illiterate.

Asia↗
PubMed1989

[Changes of glomerular fixed anionic charge sites in adriamycin nephrosis in rats].

A single intravenous injection of adriamycin (5mg per kg.) into rats induced nephrosis. In the various periods of the model, alterations of glomerular anionic sites stained with colloidal iron were analyzed quantitatively by image analyzer for the first time at home and abroad. The results showed that there was a significant decrease in glomerular anionic charge sites at 3 hours after administration of adriamycin as compared with that of the control animals (P less than 0.01). Marked loss of the anionic charge sites preceded the onset of proteinuria and was steadily increasing along with progress of the disease. The results suggest that loss of glomerular anionic charge sites may play an important role in the development of proteinuria in nephrotic syndrome.

Animals↗
PubMed1989

[The use of restriction fragment length polymorphisms for diagnosis: the estimation of diagnosable rate of more than one genetic markers].

As a codominant genetic marker, restriction fragment length polymorphisms, referred as RFLPs, has been widely applied to the prenatal diagnosis of some genetic diseases. To evaluate the usefulness of the genetic markers in prenatal diagnosis, a parameter, the diagnosable rate or the proportion of diagnosable matings is proposed in the cases of two or more genetic markers. The estimation is applicable to the cases of autosomal recessive and dominant disease, as well as those of X-linked recessive and dominant diseases. The diagnosable rate of two or more genetic markers is based on the distribution of haplotypes. Thus in the case when n genetic markers being used, the disagnosable rate, or the fraction of matings in which the A2A2 fetus could be confirmed or ruled out by the fetal restriction fragment patterns in the A1A2 X A1A2 matings, is expressed as follows: [formula: see text] where A2 is a recessive deleterious gene, yi is the frequency of the genotype of ith type individuals, and M is the total number of combination of n markers. It is a valuable strategy to use more than one genetic markers in order to increase the diagnosable rate. By using the data of the distribution of haplotypes, it is easy to find the most usable genetic markers or their combinations.

Genetic Diseases, Inborn↗
PubMed1989

[Affective disturbances in patients with breast cancer].

40 cases of breast tumor (cancer group 20 cases, benign tumor group 20 cases) hospitalized from October, 1986 to April, 1987 were investigated by interview, HAMD, SCL-90 and so on. Results showed that 10 cases met diagnostic criteria of organic affective syndrome defined by DSM-III. The morbidity of depression among all cases was 25 per cent, but the morbidity of depression in breast cancer group was higher than in benign tumor group. Causes of depression in breast cancer were analysed. Authors consider that causes of depression are not relating to operation on breast, but probably relating to biological and psychosocial factors.

Adult↗
PubMed1989

Computer simulations of figure-ground discrimination in the visual system of the fly.

Figure-ground discrimination and pattern discrimination represent one of the most important problems in computer vision. Based on computational neuronal network model proposed by Reichardt et al. for figure-ground discrimination in the visual system of the fly, entire systematic computer simulations were carried out under nonstationary conditions. Results show that the model network and simulations have predictive power for behavioural experimental results. This paper proposes that motion perception and elementary pattern discrimination in human visual system may be mediated by some kind of figure-ground system with movement detectors as input layer.

Animals↗