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Biomedical subjects

Z Liu

Publications and source records attributed to Z Liu.

At least 991 records · Page 55Linked to original sources
PubMed1996

Acute in vivo inhibition of testosterone by endotoxin parallels loss of steroidogenic acute regulatory (StAR) protein in Leydig cells.

In an experimental endotoxemia model utilizing mice, serum testosterone was found to be decreased 90% two h post ip injection of 200 micrograms of lipopolysaccharide (LPS). This decrease was sustained for 9 days. The early depression of serum testosterone was shown to be associated with a decrease in Steroidogenic Acute Regulatory (StAR) protein levels while the prolonged decrease corresponded to decreased protein and transcript levels of steroidogenic enzymes in Leydig cells. This acute and prolonged depression of testosterone production could lead to impaired spermatogenesis, accessory duct failure, and contribute to decreased male fertility following acute inflammation.

Animals↗
PubMed1996

[A comparative analysis of biological properties of glucosylrtanterases secreted by Streptococcus sanguis and Streptococcus mutans]

Our study make a comparative analysis of biological properties of glucosyltranterases(GTF) secreted by S.sanguis 34 and S.mutans Ingbritt(c).The results as follows:(1)S.sanguis 34 has more extractions of extracelluar GTF than S.mutans Ingbritt(c) under equal cultured conditions,but S.mutans Inggbritt(c) has more activity of extracelluar GTF than S.sanguis.These differences are identical with the difference of their cariogenicities;(2)GTF of S.sanguis 34 can also synthesize water-soluble glucan,and is a multienzyme complex system as S.mutans. S.sanguis might catalyse sufficient dextran formation to stimulate the primer-dependent activity of the S.mutans GTF enzyme. This might aid the adhesion of this comparatively late colonizer;(3)easier to obstruct high pure GTF of S.sangusi 34 S.mutans.

Journal Article↗
PubMed1996

[Environmental factors in oral cavity effect on growing of Streptococcus sanguis and Streptococcus mutans-effect of Mucin]

Our study use continues culture technique through adding mucin as the limiting element in chemically defined culture,medium in order to observe growing states of S.sanguis 34 and,S.mutants Ingbritt(c).The results as follows:S.sanguis 34 were able to grow as pure culture on mucin;S.mutans was unable to grow as a pure culture on mucin,but attained a significant population size in the presence of S.sanguis.These results indicate a synergetic degradation of mucin by S.sanguis and S.mutans in mixed chemism culture.

Journal Article↗
PubMed1996

[Environmental factors in oral cavity effect on growing of Streptococcus sanguis and Strepococcus mutans-Oxygen of effects]

Oral Streptococcus species belong to facultative aerobes,and are easily inhibited by metabolic products of oxygen.Our study uses continues culture technique through adding oxygen in order to observe growing states of S.sanguis 34 and S.mutans Ingbritt(c) The result is that the resistance to oxygen of S.sanguis 34 is stronger than S.mutans Ingbritt(c).This result is in accordance with the phenomenon that S.sanguis is a pioneer colonizing germ of dental plaque.The lower resistance to oxygen of S.mutans indicates that the growth and cariogenic action of S.mutans are dependent on the internal circumstance of plaque.

Journal Article↗
PubMed1996

[A preliminary study on the relationship between Streptococcus and Neisseria,Veillonella in an artificial mouth model]

The viable cell count of monobacterial plaque of Streptococcus and mixed bacterial plaque of streptococcus and Neisseria Veillonella,also the demineralization caused by the plaques were observed.The assumption that Neisseria and Veillonella might reduce demineralization of enamel caused by streptococcus was confirmed.The relationship between streptococcus and Neisseria,Veillonella were preliminarily found out.

Journal Article↗
PubMed1996

[A study on the influence of zinc on the growth and metabolism of streptococcus in an artificial mouth model]

The influence of zinc on the growth and metabolism of Streptococcus was studied under controlled conditions in an artificial mouth model.the results confirmed the previous conclusion that zinc was capable of inhibiting the growth and metabolism of streptococcus both vivo and in vitro.At the same time,the feasibility of the imitative experiments in an artificial mouth model was proved.

Journal Article↗
PubMed1996

[Quality control of zhuanggu shenjin capsules].

Studies have been made on the microscopic identification of red jinseng, dog bone, indian bread, yanhusuo and datura flower in Zhuanggu Shenjin Capsules, as well as on the identification of ginsengside and tetrahydropalmatine by TLC and the determination of icariin by dual wavelength TLC-scanning. The content of the latter compound should be no less than 0.380mg/g and the average rate of recovery 97.62% (n = 5).

Berberine Alkaloids↗
PubMed1996

Stereotactic intratumour irradiation with nuclide for craniopharyngiomas.

OBJECTIVE: Craniopharyngiomas is a kind of intractable tumor in neurosurgery. Since the radical excision is very difficult and occasionally hazardous because of its deep location and close neighbouring to critical cerebral structures, it is necessary to look for a simple and effective method. PATIENTS AND METHODS: Stereotactic intratumour irradiation with instillation of nuclide colloid was performed in 220 patients with craniopharyngiomas (altogether 265 times), of whom, 130 were male and 90 female. Their ages ranged from 5 to 69 years. The syndromes of optic path's impairment were present in all of the patients. CT or MRI scan showed cystic tumour in 125 patients, solid and cystic in 80 and solid in 15. No severe complications and death were related to the operation. RESULTS: 150 patients were followed up for 2 months to 7 years (average 3.5 years). Tumours disappeared in 92 patients (61.4%), decreased dramatically in 20 (13.4%), decreased less than 50% in 19 (12.6%), and increased in 15 (10%); and there were 4 deaths (2.6%). CONCLUSIONS: Stereotactic intratumour irradiation with instillation of nuclide colloid is effective in the patients with craniopharyngiomas. Beta-emitting isotopes (P-32 and Y-90) are the preferred internal radiation source because of their limited penetration of the energy released and the greater ease of handling. A calculated dose of 20 000 rads to the cyst wall is recommended.

Adolescent↗
PubMed1996

Evaluation of the redox tolerance index on hepatic energy reserve of hepatitis B patients.

OBJECTIVE: To detect the redox tolerance index (RTI) for hepatic energy reserve. PATIENTS AND METHODS: 27 patients with chronic active hepatitis B (CAH) and 34 patients with post-hepatitis B liver cirrhosis (LC) were studied. RESULTS: The RTI was significantly lower in CAH and LC cases than in normal controls (P < 0.01). There was no difference between CAH and LC. The RTI of decompensated LC was significantly lower than that of the compensated LC (P < 0.05), indicating that there was no correlation between RTI and the parameters of routine liver functions. CONCLUSION: It is suggested that the RTI based on redox theory is effective and accurate in predicting hepatic energy reserve.

Adult↗
PubMed1996

[Inducing effect of dimethy-4, 4'-dimethoxy-5, 6,5',6-dimethylenedioxybipheny-2, 2'-dicarboxylate (DDB) on differentiation of leukemia HL-60 cells].

OBJECTIVE: To study the effects of anti-hepatitis drug, DDB, on leukemia cell line HL-60. METHOD: Cytobiological methods were used. RESULT: DDB was inhibited the proliferation of HL-60 cells. About 50% of HL-60 cells treated with DDB (10(-4)mol/L) for 6 days exhibited NBT reduction, and phagocytosis activity was also enhanced by DDB (10(-4)mol/L) for 4 days. The HL-60 cells treated with DDB turned out to be mature granulocytes morphologically. CONCLUSION: The activity of acid phosphatase in DDB-treated HL-60 cells was significantly increased. DDB can induce HL-60 cells to differentiate along granulocyte lineage.

Acid Phosphatase↗
PubMed1996

[Using a lipid clearing drug to prevent osteocytes damage of the femoral head in steroid-treated rabbits].

OBJECTIVE: We investigated experimentally the prevention of steroid-induced osteonecrosis of the femoral head. METHODS: Twenty-three rabbits were divided into three groups: (Group S) steroid treated, (Group T), steroid and clofibrate treated, and controls. Serological tests (cholesterol and triglyceride), histology and histochemical studies and electron microscopic examination were performed six weeks after treatment. RESULTS: The serum cholesterol and TG levels increased obviously in Group S. Although Group T animals also showed hyperlipidemia, their serum cholesterol and TG levels were much lower than those for Group S. Group S animals demonstrated fatty degeneration of the liver. Lipid droplets were seen in the osteocytes of the femoral heads of these animals, which compressed the nucleus of the osteocytes along with nuclear pyknosis or absent nuclei. However, the construction of liver cells and osteocytes of the femoral head were almost normal in Group T. Lipid containing osteocytes were not seen in these animals. CONCLUSION: These observations demonstrated that clofibrate decreased hyperlipidaemia, modified lipid metabolism, and diminished steroid-induced damage to the osteocytes. This finding may be a guide to protect against steroid-induced osteonecrosis of the femoral head.

Animals↗
PubMed1996

[Clinical application of intraoperative sustained limited expansion].

Since May 1993, the technique of intraoperative sustained limited expansion (ISLE) had been applied clinically in 21 cases for the immediate reconstruction of soft tissue defects. Satisfactory results were obtained in 18 cases (85.7%), and failed in 3 cases (14.3%). ISLE had been applied successfully in various regions of the body. It had been shown that the results were dependent on the extent of soft tissue defect, the extent of intraoperative tissue gain, and the time of intraoperative sustained expansion.

Adolescent↗
PubMed1996

[Clinical and experimental studies on zhikang oral liquid in treatment of hypophrenia].

The effect of Zhikang Oral Liquid (ZK) on 50 cases of hypophrenia children was observed and a control group of 20 cases was set. Results showed that the total effective rate of ZK group was 82%, it was significantly higher than that of control group (P < 0.01). Animal experiment revealed that ZK could improve the hypomnesia in learning caused by anisodine, poor memory retention caused by sodium nitrite and memory hypo-reproducibility caused by 40% alcohol. The results of clinical and experimental studies suggested that ZK could promote the intelligence development of child and improve the memory.

Adolescent↗
PubMed1996

[Rapid detection of Salmonella with MUCAP reagent].

The 4-methylumbelliferyl-caprylate (MUCAP) was applied for the identification of Salmonella, it's specification, sensitity, and availability were reported. 65 strains of standard Salmonella, 48 strains of Salmonella isolated from foods growing on plates of HE, DHL, SS and MaConkey agar have been tested with MUCAP. All of them were identified as MUCAP positive; whereas, among the non-Salmonella tested only Pseudamonas spp., Aeromonas hydrophilia and Plesiomonas shigelloides were shown as positive, but they could be differentiated easily with Salmonella by means of oxidase test. The unspecific reaction of Serratia marcescens could be eliminated by using the plate medium which has been added of 1% sucrose. Both the sensitivity and specificity of the method were up to 97% more, and the operating of the method was very facility and to be done within few minutes.

Hymecromone↗