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Biomedical subjects

Z Jienescu

Publications and source records attributed to Z Jienescu.

At least 19 recordsLinked to original sources
PubMed1980

[Epidemiological study of chronic bronchitis in a population sample aged 60-85 years: contributions to the study of the natural history of chronic bronchitis (author's transl)].

An epidemiological study was undertaken by means of the MRC questionnaire on respiratory symptoms and of spirographic tests (VC and FEV 1.0) in a population of elderly people (374 men and 377 women 60-85 years old) examined periodically during the last 10 years. In a large number (39,2%) of smokers who had persistent cough the spirographic values were normal. (The reference values for VC and FEV 1.0 were obtained by means of regression equations developed from samples of subjects belonging to the same age-group who had no history or symptoms of respiratory disease).

Aged↗
PubMedDate not supplied

[Contribution of pulmonary scintiscanning to the diagnosis of chronic obstructive bronchopneumopathy].

In a lot of 32 cases of chronic obstructive bronchopneumopathy, a correlation was established between the extent and location of the regional perfusion deficiencies (studied by scintigraphy) and overall functional disturbances Vmax MEVS X 100VC, residual volume, R, PaO2, PaCO2). In 85% of the cases regional perfusion disturbances were detected and grouped into six scintigraphic types. A good correlation was found between these disturbances and the MEVS X 100/VC index and modified partial pressure of the gases (O2, CO2) in the arterial blood. Unexpected was the absence of a mathematical correlation between perfusion disturbances and the residual volume and R, suggesting the great variety of the disturbances grouped under the general denomination of chronic obstructive bronchopneumopathy.

Adult↗
PubMedDate not supplied

[Prevalence of chronic productive cough and obstructive ventilatory dysfunction in a rural community with minimal air pollution].

Results obtained during an epidemiological investigation on chronic cough and obstructive ventilatory dysfunction in subjects without bronchopulmonary affections of known etiopathogeny, carried out in a rural environment with minimal air pollution on 282 men aged between 40 and 69 years, indicate the following: --there was a lower prevalence of chronic cough in the rural environment as compared with the urban one (12.8:21.0). The percentage of heavy smokers being approximately similar in both environments, the difference could be explained by the variable intensity of air pollution, the impact of which was exerted on the large airways (hypertrophy of the serous-mucous glands resulting in hypercrinia with dyscrinia); --similar prevalence in the two environments of the obstructive ventilatory dysfunction (11,0:8,7) suggests that this abnormality, an expression of the narrowing of the small airways, could be due to other pathogenic factors. Functional pulmonary tests with sensitivity higher than the ratio between FEV 1.0 and VC (as, for instance VEmx 50% VC) could provide higher percentages of obstructive disturbances both among chronic coughing and non-coughing subjects, revealing the latent form of the obstruction, as opposed to the manifest one as evidenced by a decrease of the FEV 1.0/VC ratio.

Adult↗
PubMedDate not supplied

[Epidemiological study of chronic cough and obstructive ventilatory dysfunction in a rural area].

An epidemiological study (MRC--Questionnaire and spirography) has been carried out on a population aged between 40 and 69 years living in a rural area (Costeşti, district of Buzău). 440 subjects (202 men and 238 women; 83% of the population in this age group) were examined. Chronic productive cough in subjects with no other respiratory diseases was found in 8,9% of the examinated males and in 5.0% of the females. The figures are lower than those found in an urban population and in a previous survey in an other rural area. Obstructive syndrome (reduced FEV 1.0/VC ratio) was found in 5.0 and in 2.9%, respectively. More than half of the patients with obstructive syndrome had no cough; the lung function alterations found in these subjects may be due--at least in some cases--to the obstruction of distal airways which have no clinical manifestations in the early stages.

Adult↗
PubMedDate not supplied

[The time variations in pulmonary functional parameters in children with bronchial asthma].

28 children with bronchial asthma, between 6 and 18 years old, were followed by a varied period of time - 3 months - 5 years. 7-8 functional tests were carried out. The cases were studied in different clinical phases: asymptomatic, manifest, crisis of bronchial asthma. The functional pulmonary investigation included: spirographic examination [vital capacity (VC), maximum expiratory volume per second (MEVS) the VC/MEVS ratio], plethysmographic examination (VGT, Raw), measurement of the maximum instantaneous expiratory flows on the flux-volume curve (MEF50). The average value, standard residual deviation and the variation coefficient were calculated for each parameter studied in different clinical moments. The results are presented on 3 groups: per total, symptomatic and asymptomatic. The analysis of the data found showed that the variation of the parameters measured during repeated functional examinations in children with bronchial asthma ranges within broad limits (2.9%-11.5%); the broadest variation was recorded for Raw followed by MEF50 and the slightest variation was that of the VC/MEVS ratio. This indicated the lower value of the information furnished by this ratio in children, in appreciating the presence or severeness degree of the obstructive syndrome.

Adolescent↗
PubMedDate not supplied

Pulmonary mechanics in patients with diffuse interstitial lung disease and normal lung volume.

Static expiratory pressure-volume curves obtained in 20 patients with diffuse interstitial lung disease and lung volume within normal ranges (i.e. in patients in an early stage of the disease) showed different patterns of abnormal lung elastic recoil: 1) P-V curves with normal shape but shifted to the right, which suggest an overdistension of a reduced number of functioning alveoli ("lung shrinkage") and 2) flattened P-V curves (i.e. with low static compliance) also shifted to the right, which argue for an abnormal distensibility of most alveoli or a more diffuse spreading of lesions. These patterns suggest a multifactorial genesis of the increased elastic recoil in diffuse interstitial lung disease.

Adult↗
PubMedDate not supplied

[The relation of severe obstructive disorders to ventilation found in young patients with bronchitis and bronchopulmonary diseases in childhood].

Of the patients with chronic obstructive pulmonary disease (COLD) and severe obstructive syndrome, 39 whose age was under 40 were selected. In 23 of them, the anamnesis revealed bronchopulmonary affections in childhood, that required admission into the hospital (19 were non-smokers). Of the rest of 16 patients, 14 were hard smokers that started to smoke before the age of 14. The functional picture was severely modified, similarly to that of the COLD patients in the 6th decade of life. This suggests that the degradation process started in the childhood, and that the chronic respiratory diseases and/or smoking at an early age had an important role.

Adolescent↗
PubMedDate not supplied

[Pulmonary functional criteria for evaluating the evolution of diffuse interstitial pneumopathy under treatment].

It was studied the variation of the pulmonary volumes, of the gaseous transfer through the alveolocapillary membrane and of the indications of pulmonary elasticity on 40 patients with diffuse interstitial lung disease (PID), examined at intervals of 3-6 months, for 2-3 years during the treatment. The levels of the pulmonary elasticity parameters have signaled more frequently the modification (improvement or worsening) of the pulmonary functional state than those of the pulmonary volumes or of the gaseous transfer. Hence the proposal of including the tests for elastic recoil within the ensemble of pulmonary functional investigations through which are studied the effects of the treatment prescribed in PID.

Adolescent↗