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Biomedical subjects

Y Weiss

Publications and source records attributed to Y Weiss.

At least 73 records · Page 4Linked to original sources

The meaning of dopamine beta-hydroxylase in essential hypertension.

1. Resting plasma dopamine beta-hydroxylase (DBH) activity and haemodynamic parameters were studied in untreated borderline (twenty-nine) and permanent (twenty-seven) essential hypertensive patients. DBH was also measured in sixty-three apparently healthy subjects. 2. Mean DBH values were not significantly different between the groups. 3. Cardiac output, cardiopulmonary blood volume and the cardiopulmonary blood volume/total blood volume ratio (CPBV/TBV) were significantly higher in borderline than in permanent hypertensive patients. 4. In borderline hypertensive patients, plasma DBH activity was directly correlated with diastolic arterial pressure and with values of cardiac output, cardiopulmonary blood volume and CPBV/TBV ratio. No such correlations could be observed in the permanent hypertensive group. 5. These results suggest that plasma DBH activities in borderline hypertension mainly depend on the sympathetic activity responsible for the haemodynamic variations. Contrariwise, plasma DBH activities in permanent essential hypertensive patients appear to reflect other factors.

Adolescent↗

A method for reducing the incidence of infusion phlebitis.

A departmental routine has been evolved wherein intravenous infusions are administered for a maximum daily period of 12 hours. Exceptions are made for patients with poor peripheral veins. Results of a prospective study of 376 patients for a period of one year demonstrated a markedly reduced incidence of thrombophlebitis, namely, 4.4 per cent in 297 patients treated by the intermittent method versus 20.3 per cent in 79 patients who received continuous intravenous infusion therapy for more than 24 hours.

Catheterization↗

[Use of propranolol in permanent essential hypertension].

The anti-hypertensive effect of propranolol is studied in 35 essential permanent hypertensive patients. The decrease in blood pressure in higher in the presence (p is less than 0.01) than in the absence of diuretic therapy. The anti-hypertensive effect is higher in severe than in moderate hypertension. No side effect was observed except the decrease in heart rate (p is less than 0.001). Dihydralazine was added in 4 severe hypertensive patients and induced in 2 of them anginal attacks.

Adult↗

Immune complex type glomerulonephritis in cirrhosis of the liver.

Glomerular lesions were detected in 9 of 10 patients with liver cirrhosis: these lesions consisted of a) thickening of basement-membrane-like material, b) electron-dense deposits in mesangial areas and in capillary walls, c) round areas of rarefaction in the membrane-like material and in some deposits, and d) presence of IgA, with IgG and/or IgM and/or C3, in the deposits. The association of these four abnormalities seems to be characteristic of "cirrhotic glomerulonephritis." The deposits could be the result of precipitation in the glomeruli of either aggregated immunoglobulins or circulating immune complexes.

Adult↗

[Electrocardiography of the hypertensive patient: correlations with hemodynamic parameters].

A comparative study between electrocardiographic signs of left ventricular hypertrophy and haemodynamic parameters is performed in 184 permanent hypertensive patients. They are divided into 3 groups taking into account the level of electrocardiographic changes. Patients with a normal electrocardiogram have a slight increase in arterial pressure, an increase in cardiac index (P is less than 0.01) and total peripheral resistances (P is less than 0.001) and a reduction of plasma volume (P is less than 0.001). Patients with a moderate change in their electrocardiogram have normal cardiac output, high peripheral resistances (P is less than 0.001) and a slight decrease in plasma volume (P is less than 0.05). Patients with a left major ventricular hypertrophy have a reduced cardiac output (P is less than 0.01), increased peripheral resistances (P is less than 0.001) and a normal plasma volume. The significance of such facts, especially concerning the hemodynamic response in upright position, is discussed.

Adult↗

Spigelian hernia.

Nine cases of Spigelian hernia treated during a period of five years are presented. The literature is reviewed and the importance of recognizing the condition is stressed. The main pathological and clinical features are discussed.

Adult↗