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Biomedical subjects

Y Tanabe

Publications and source records attributed to Y Tanabe.

At least 361 records · Page 20Linked to original sources
PubMed1979

A cause of paired ventricular extrasystoles.

Eight patients with ventricular extrasystoles are reported in whom coupling intervals of the extrasystoles to the proceding sinus beats were variable and in whom paired ventricular extrasystoles were occasionally seen. In all patients, paired ventricular extrasystoles were initiated only by comparatively late coupled ventricular extrasystoles. However, the interval between the first and the second of these paired extrasystoles was always much shorter than the coupling interval of this first extrasystole to the preceding sinus beat, so that the latter extrasystole often interrupted the T wave of the first one, indicating the R-on-T phenomenon. In two patients there was a gap between the ranges of coupling intervals for single extrasystoles and for the first ones of paired extrasystoles. These observations suggest the presence of longitudinal dissociation in the reentrant pathway as one of the causes of paired ventricular extrasystoles.

Adult↗
PubMed1979

Mitochondrial glutamic oxaloacetic transaminase and its clinical significance.

The m-GOT were studied in 57 patients with liver diseases, diagnosed by peritoneoscopy and biopsy. In acute hepatitis, the m-GOT rose to 100 units or there-about. But in chronic hepatitis, even in hepatitis B with sublobular necrosis, the m-GOT were low and 20--30 units. On the other hand, in alcoholic hepatitis, the m-GOT were 50--60 units which may be considered to be higher than expected for comparable their histological necrotic findings. These values were higher than OCT, which were measured at the same time. This results showed that there might be m-GOT induction by alcohol. In liver cirrhosis lower values were obtained. Generally m-GOT was liable to be lower as the lobular distortion was getting severer.

Adult↗
PubMed1978

Genetic variants of hemoglobin in canine erythrocytes.

Genetic polymorphism of hemoglobin was found in the erythrocytes of dogs of seven Japanese native breeds by using starch gel electrophoresis. Analysis of parentage records of the dogs revealed that the phenotypic variation of hemoglobin is controlled by one autosomal locus with two codominant alleles, HbA and HbB. the allele HbA occurred only in Japanese native breeds except Shikoku. The frequency of HbA in the Japanese breeds was low and 0.08. All the dogs belonging to 25 European breeds and 5 oriental origin (except Japan) breeds examined in this experimnets had the homozygous genotype constitution HbB/HbB.

Alleles↗
PubMed1978

Concealed (proximal) Wenckebach phenomenon with distal 2:1 exit block in the ectopic-ventricular junction.

The findings in two patients with interpolated ventricular extrasystoles showing 2:1 exit block are reported. In these patients the blocked impulses appear to penetrate into the ectopic-ventricular junction (or reentrant pathway) to a varying extent, and the coexistance of a distal 2:1 exit block and a proximal (concealed) Wenckebach phenomenon in the ectopic-ventricular junction is suggested.

Cardiac Complexes, Premature↗
PubMed1977

Administration of prostaglandin F2alpha for the recovery of fertilized eggs from the vaginas of rabbits.

Nonsurgical recovery of fertilized eggs from the vaginas of prostaglandin F2alpha (PGF2alpha)-treated rabbits was attempted. Eighty-two eggs were collected by the vaginal washing method, and the earliest egg was recovered 20 hours after mating. Twenty eggs recovered vaginally 24 to 107 hours after mating were transferred to six synchronized, pseudopregnant rabbits to test the viability of the eggs; four newborns, two fetuses, and one implantation site were obtained. These results indicate that some viable eggs are discharged into the vaginas of rabbits treated with PGF2alpha.

Animals↗
PubMed1977

Genetic polymorphism of eserine resistant esterases in canine plasma.

Six plasma eserine resistant esterase phenotypes were observed in a population of 1438 dogs consisting of 38 breeds. Analysis of parentage records of the dogs examined revealed that the phenotypic variation of eserine resistant esterases was controlled by 3 codominant alleles ESA, ESB and ESC at one autosomal locus. The gene frequency of ESB was high in most of the breeds examined. Allele ESC was only seen in 5 Japanese native breeds, Akita, Shikoku, Hokkaido, Shinshu-Shiba and Mino-Shiba, and in a Spitz dog. Allele ESA has a low frequency in Japanese breeds but a higher frequency in some of the European breeds tested.

Alleles↗
PubMed1977

Genetic variants of glucose phosphate isomerase (E.C. 5.3.1.9) in canine erythrocytes.

Genetic polymorphism of glucose phosphate isomerase (GPI) was found in the erythrocytes of dogs of six Japanese breeds by using starch gel electrophoresis. Analysis of parentage records of dogs revealed that the phenotypic variation of erythrocyte glucose phosphate isomerase was controlled by one autosomal locus with two codominant alleles, GPIA and GPIB. The allele GPIB was observed in the following breeds: San'in-Shiba, Shinshu-Shiba, Shikoku, Kai and Kishu, but not in Hokkaidoes and Akitas. All the dogs belonging to 25 European breeds, 5 oriental or China-origin (except Japan) breeds examined in this experiments had the genotype constitution GPIA/GPIA, whereas one Dalmation dog was heterozygous GPIA/GPIB.

Alleles↗
PubMed1976

Origin of sequence heterogeneity of the small subunit of fraction 1 protein from Nicotiana tabacum.

The partial amino acid sequences of the small subunit of Fraction 1 protein from N. sylvestris, N. tomentosiformis and N. tabacum were determined. The sequence of N. sylvestris is NH2. Gln-Val-Trp-Pro-Pro-Ile-Asn-----Tyr COOH. In the sequence up to the 7th amino acid and C-terminus, differences were only found at the 6th position in the three species, where N. sylvestris and N. tomentosiformis show Ile and Tyr, respectively. N. tabacum show both Ile and Tyr in almost equal amount at this position. These results confirmed a previous hypothesis that N. tabacum had been evolved through the hybridization of N. sylvestris and N. tomentosiformis.

Amino Acid Sequence↗
PubMed1976

Origin of Nicotiana tabacum detected by primary structure of fraction I protein.

Nicotiana tabacum is believed to have arisen after hybridization of Nicotiana sylvestris with a species in the Tomentosae section of the genus Nicotiana. Recent biochemical experiments have confirmed the conclusions from previous cytogenetic studies that N. sylvestris was the maternal parent and have indicated that Nicotiana tomentosiformis was the paternal parent. However, these studies did not take into account the possibility that a new species of Nicotiana, called K-12, discovered in South America in 1968, could also have been one of the parents. Fraction I proteins were purified from N. tabacum and its putative progenitors, and separated into large and small subunits. Chymotryptic peptides of each subunit were analyzed by ion exchange column chromatography with a gradient elution system. Among 38 resolved peaks of the large subunits, 2 peaks were found to be different among the putative species. Since only N. sylvestris showed an identical chromatogram with N. tabacum, N. sylvestris was concluded to be the maternal progenitor, as the genetic information for the large subunit of Fraction I protein was known to be inherited by the cytoplasmic mode. On the other hand, the small subunit of Fraction I protein is inherited by the Mendelian mode and therefore N. tabacum, an allopolyploid, could be expected to contain two types of small subunits, one derived from N. sylvestris and the other from a paternal progenitor. N. sylvestris lacks two of the 25 chymotryptic peptides of the small subunit of N. tabacum. Among 3 putative paternal progenitors, these two peaks appeared only in N. tomentosiformis, but not in Nicotiana otophora or K-12. Thus, N. tomentosiformis was concluded to be a paternal progenitor of N. tabacum. The conclusion was verified by comparing chymotryptic peptides of small subunits from three amphidiploids of N. sylvestris crossed with N. tomentosiformis, N. sylvestris crossed with N. otophora snd N. sylvestris crossed with K-12. The analytical results showed that only the progeny of N. sylvestris crossed with N. tomentosiformis contained the same small subunits as N. tabacium.

Chymotrypsin↗
PubMed1976

Cystic goiter with squamous-cell metaplasia--case report and comment on origin of squamous-cell cyst.

A 53-year-old woman with a left unilocular cystic goiter of the size of a small orange was reported. Approximately four-tenths of the innter surface was lined with several layered squamous epithelium with few follicles remaining. A gradual metaplastic transition from the follicular epithelium to the flattened cuboidal and to the squamous epithelium was observed. The ultimobranchial body has been understood to be a possible origin of an entirely squamous cell cyst of the thyroid, three of which have been reported. The difference between the ultimo-branchial and metaplastic origins will be discussed, and a new designation-primary (ultimo-branchial) and secondary (metaplastic) squamous-cell cyst will be proposed.

Animals↗