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Biomedical subjects

Y Takeuchi

Publications and source records attributed to Y Takeuchi.

At least 1,081 records · Page 60Linked to original sources
PubMed1980

Distribution of cerebellothalamic neurons projecting to the ventral nuclei of the thalamus: an HRP study in the cat.

Distribution of cerebellothalamic neurons projecting to the ventral nuclei of the thalamus was examined in the cat, using the horseradish peroxidase (HRP) method. After injections of HRP within the lateral or ventrolateral portions of the ventro-anterior and ventrolateral nuclear complex of the thalamus (VA-VL), neurons labeled retrogradely with HRP were seen contralaterally in the cerebellar nuclei; many of them were situated in the nucleus interpositus anterior and nucleus interpositus posterior, and a moderate number of them were located in the nucleus lateralis. Labeled neurons in the nucleus interpositus posterior were observed mainly in the medial and ventral portions of the nucleus. On the side ipsilateral to the injections, a few labeled neurons were seen in the nucleus interpositus anterior, nucleus interpositus posterior, and nucleus lateralis. Virtually no labeled neurons were found in the nucleus medialis of the cerebellum. After HRP injections into the medial or dorsomedial portions of the VA-VL, many labeled neurons were found contralaterally in the ventral and ventrolateral portions of the nucleus interpositus posterior, as well as in the nucleus lateralis, especially in its ventral and lateral portions. On the side ipsilateral to the injections, labeled neurons in the nucleus lateralis and nucleus interpositus posterior were small in number. In the nucleus medialis only a few labeled neurons were found bilaterally in the caudal levels of the nucleus. After HRP injections centered on the ventromedial nucleus of the thalamus, many labeled neurons occurred bilaterally in the caudal portions of the nucleus madialis, with a slight contralateral preponderance, and contralaterally in the lateral and ventral portions of the nucleus lateralis. A few labeled neurons were also seen contralaterally in the ventrolateral and lateral portions of the nucleus interpositus posterior, and ipsilaterally in the nucleus lateralis.

Animals↗
PubMed1980

The role of electrogenic pump in Chara corallina.

The conductance, G, and the electromotive force, E, of the Chara membrane were determined accurately by using the current-clamp technique. The measurements at the final steady state of inhibitor poisoning give the conductance, g1, and the electromotive force, E1, of the passive ion conducting pathways. By knowing these values the conductance, g2, and the electromotive force, E2, of the electrogenic pump can be calculated from the measured G and E at each time during the progress of inhibitor poisoning. The local closed circuit current, i, which usually causes a hyperpolarization across the passive conducting pathways, can be calculated by using g1, g2, E1 and E2 thus determined. The values of g2 and i decrease monotonically to zero with the progress of poisoning, while E2 approaches E1 asymptotically after a transient hyperpolarization. During excitation i increases markedly. Such an increased inward current through the passive conducting pathways may help in accelerating the inactivation of the excitatory mechanism.

Action Potentials↗
PubMed1980

Inhibition of metabolic responses to surgery with beta-adrenergic blockade.

Glucose, lactate, non-esterified fatty acid and insulin levels in plasma were measured in two groups of 12 patients undergoing gastrectomy under general anaesthesia. Propranolol in a dose of 0.3 mg/kg body weight was intraoperatively infused in one of the two groups. Surgery under general anaesthesia elicited a significant rise in blood glucose, lactate and NEFA concentrations. These metabolic responses were significantly inhibited by intraoperative infusion of propranolol without producing any undesirable side effect. Plasma insulin levels showed a slight decrease during the operation and no significant difference was noted between the two groups. The results suggest that beta-adrenergic activity is playing a major role in these metabolic responses, promoting the mobilization of substrates. Possible benefits of inhibiting beta-adrenergic activation in surgical stress are discussed.

Blood Glucose↗
PubMed1980

Non-selective distribution of hypoglossal nerve fibers after section and resuture: a horseradish peroxidase study in the cat.

The retrograde tracing method of horseradish peroxidase (HRP) was applied to examine the process of regeneration of severed hypoglossal nerve in the cat. After section and resuture of the hypoglossal nerve, the cats were allowed to survive for 4-6 months. In these cats, distribution of neurons labeled with HRP injected into the genioglossus muscle was examined and compared with that in the normal cat. In the operated cats, labeled genioglossus motoneurons were scattered within all subdivisions of the hypoglossal nucleus, indicating non-selective distribution of regenerating hypoglossal nerve fibers to the lingual muscles.

Animals↗