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Biomedical subjects

Y Tabata

Publications and source records attributed to Y Tabata.

At least 181 records · Page 10Linked to original sources
PubMed1986

Immobilization of collagen onto polymer surfaces having hydroxyl groups.

The cyanogen bromide (CNBr) activation method was adopted to link collagen molecules onto the surface of cellulose and poly(vinyl alcohol) (PVA) films via covalent bonding. The amount of bound protein was determined by the ninhydrin method and found to be 1.0 microgram/cm2 for the native collagen and 0.6 microgram/cm2 for the denatured collagen. The amount of bound protein was larger for cellulose than PVA. When p-toluene-sulphonyl chloride was used to activate the cellulose film, this activation method was found to be effective in grafting the collagen as well. The cellulose film was found to become brittle and weak after activation with CNBr, but the PVA films was not. This might be due to the difference in the extent of crosslinking between cellulose and PVA films, as demonstrated by the change in degree of swelling and solubility of both the activated films.

Biocompatible Materials↗
PubMed1986

[Retroperitoneal liposarcoma with various histological figures].

A case of retroperitoneal liposarcoma consisting of three large nodules with three different types of histologic findings is presented. A 69-year-old man was diagnosed as having a malignant tumor in the retroperitoneum and underwent successful tumor extirpation. The resected tumor had three different type of nodules, 18 X 15 X 7.0 cm, 8 X 15 X 4.0 cm, 15 X 10 X 2.5 cm in size, respectively. The histologic examination revealed myxoid, well-differentiated fibrosing and lipoma-like liposarcoma type, respectively. Chemotherapy was undertaken postoperatively, and there is no evidence of recurrence two years after surgery.

Aged↗
PubMed1985

[Thermotherapy for cancer of the urinary bladder in combination with tegafur suppository and picibanil--concentrations of tegafur in the serum and tissues in bladder carcinoma].

Thermotherapy combined with tegafur (FT-207) and Picibanil was performed in 13 patients with cancer of the urinary bladder. The thermotherapy was performed using a closed circulation type of thermotherapeutic apparatus manufactured for this experiment, by way of a 3-way catheter. The flow rate of the perfusate was 150 ml/min at a constant temperature of 43 degrees C. The temperature was monitored at the inlet and outlet catheter of the urethral meatus. The thermotherapy was performed for a 6-hour period once a week. A tegafur 3000-mg suppository was given 2 hours before the thermotherapy, and Picibanil was added to the perfusate at the time of thermotherapy. No anesthesia was used. Complete disappearance of the tumor was observed in 1 case. The concentrations of tegafur in the serum, tumor and bladder wall were measured simultaneously. The levels obtained at two hours after rectal administration of the tegafur 3000-mg suppository were 19.420 mcg/ml for FT-207 and 0.025 mcg/ml for 5-FU in the serum, 13.170 mcg/g for FT-207 and 0.140 mcg/g for 5-FU in the bladder tumor, and 20.447 mcg/g for FT-207 and 0.252 mcg/g for 5-FU in the bladder wall. Eruption was observed in 1 case. No other side effects were noted.

Adult↗
PubMed1983

Causes of death of diabetic patients in the past 10 years and their ECG findings.

We investigated the causes of death of 98 subjects with diabetes mellitus over the past 10 years at our hospital. As was expected, the cause with the highest incidence (48.0%) was vascular disease including cerebral vascular disease (20.4%), coronary heart disease (15.3%), aortic disease and miscellaneous (3.1%), followed by malignant tumors (39.8%), infectious diseases (4.1%) and other diseases. Only one patient died from diabetic coma. The abnormal ECG findings of these patients were analyzed according to the Minnesota Code and 57%, 31%, 26%, 24%, 19% of them showed arrhythmias, ST-T abnormalities, LVH, VPC, and abnormal Q-wave, respectively. These findings showed no statistical difference between diabetics and non-diabetics. Abnormal p-wave, especially LA-load was found more often in diabetics (35%) than in non-diabetics (21%). Q-T interval corrected by Bazett's formula (Q-Tc) was 430 +/- 3.03 (M +/- SEM) msec in diabetics and it was significantly longer (p less than 0.01) than 417 +/- 3.73 msec in patients with other diseases.

Adult↗