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Biomedical subjects

Y Shoenfeld

Publications and source records attributed to Y Shoenfeld.

At least 811 records · Page 45Linked to original sources
PubMed1981

Cholinergic urticaria. A seasonal disease.

Nine young patients with cholinergic urticaria reported that the occurrence of the disease was restricted to winter. They were examined in a climatic room in winter and summer under three climatic conditions in each season (cold, comfort, and severe heat). All subjects experienced severe phenomena of cholinergic urticaria during the winter season when tested under comfortable climate and under severe heat load. No phenomena were elicited in the summer under any of the three climatic conditions or under cold climatic condition in the winter. This finding led to the assumption that symptoms appear in the sufferers only when exposed to heat or heat-producing exercise while unacclimatized to heat. Artificial heat acclimatization is winter resulted in disappearance of all clinical phenomena of cholinergic urticaria, lasting from a few days to two weeks.

Adult↗
PubMed1981

Prednisone-induced leukocytosis. Influence of dosage, method and duration of administration on the degree of leukocytosis.

The long-term pattern of prednisone-induced leukocytosis was examined in 80 patients. Our results disclosed an extremely variable leukocytic responses, in which the white blood cell count surpassed 20,000/mm3 as early as the first day of treatment, an increase that persisted for the duration of therapy. Although the degree of leukocytosis was related to the dosage administered, it did appear sooner with higher doses. Leukocytosis reached maximal values within two weeks in most cases, after which the white blood cell count decreased, albeit not to pretreatment levels. The leukocytosis was attributed predominantly to a rise in the polymorphonuclear white blood cells, a phenomenon that coincided with monocytosis, eosinopenia and a variable degree of lymphopenia. It can be concluded that even small doses of prednisone, administered over a prolonged period of time, can induce extreme and persistent leukocytosis. This observation is of consequence especially when infection is suspected, particularly in an immunocompromised host. However, a shift to the left in the peripheral white blood cells, i.e., more than 6 percent band forms, and the appearance of toxic granulation may assist in the differential diagnosis between infection, in which the latter are observed, and corticosteroid-induced leukocytosis, in which they are rare.

Dose-Response Relationship, Drug↗
PubMed1981

Effect of physical effort on the white blood cells in benign familial leukopenia.

The components of the peripheral white blood cells (WBC) were determined before and after 10 min of submaximal ergometric work in two groups of subjects: 34 healthy Yemenite Jews with benign familial leukopenia (BFL) and 34 healthy Yemenite Jews without BFL. The mean +/- SEM of the increase in the peripheral WBC following the effort in the control group was 2,606 +/- 1,272 cells/mm3, due to the relative rise in the neutrophils, eosinophils, monocytes and lymphocytes. The identical ergometric work, performed by BFL subjects, brought about significantly lower increase (700 +/- 865 cells/mm3) in the peripheral WBC, the majority of which were lymphocytes. It seems that subjects with this form of BFL lack granulocytes in the marginal pool.

Adolescent↗
PubMed1981

The relationship between body temperature and intraocular pressure.

A comparison of the intraocular pressures of well-hydrated nonacclimatized and acclimatized subjects during submaximal work load in a hot environment was made. This comparison attempts to eliminate all possible influences on IOP, except body temperature. A direct relationship between the IOP and rectal temperature is postulated.

Acclimatization↗