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Biomedical subjects

Y Scharf

Publications and source records attributed to Y Scharf.

At least 55 records · Page 3Linked to original sources
PubMed1980

HL-A antigen in Sjögren's syndrome.

The association between Sjögren's syndrome and the HL-A system is still a matter of controversy, because there are conflicting data as to whether this syndrome is linked with HL-A B8 and Dw3. In an attempt to study this possible linkage, a survey of HL-A antigens among a homogenous group of East European (Ashkenazi) Jews was undertaken. The tissue typing of 30 patients with sicca syndrome (SS), 18 patients with rheumatoid arthritis and Sjögren's syndrome (RASS), and 80 healthy controls of the same ethnic group was analyzed. Neither sicca syndrome nor rheumatoid arthritis with Sjögren's syndrome was associated with HL-A B8 or any other antigen. The difference between our results and previous studies is discussed.

Adult↗
PubMed1978

Sialochemistry of patients with rheumatoid arthritis. Electrolytes, protein, and salivary IgA.

Sialochemistry was undertaken to detect subclinical involvement of salivary glands in patients with rheumatoid arthritis (RA). The concentrations of salivary sodium and IgA were significantly elevated in 24 percent of the RA patients. Eighty per cent of the patients with elevated sodium and IgA concentrations had keratoconjunctivitis sicca as well. No correlation between serum and salivary IgA levels was found. The results indicate that salivary sodium and IgA levels can be used for detection of subclinical salivary gland involvement and for follow-up of RA patients.

Adolescent↗
PubMed1978

HL-A antigens in Behçet's disease. A family study.

Histocompatibility antigens (HL-A) were studied in a family with Behçet's disease (BD). All who had symptoms or signs of BD had either HL-A B5 or BW35, or both. The increased number of families with BD recently reported supports the suggestion that positive family history may assist the diagnosis of BD.

Adolescent↗
PubMed1977

HL-A as a diagnostic aid in incomplete rheumatic syndromes.

Incomplete Reiter's syndrome (ICRS) and incomplete Behçet's disease (ICBD) have many similar clinical features, making the diagnosis difficult. The association of RS and BD with different HL-A antigens is a help in differentiating between the two diseases. Eight patients with incomplete rheumatic syndrome are described. The results of HL-A typing suggest that five patients had incomplete RS and the other three incomplete BD. The value of tissue typing in the correct diagnosis of incomplete rheumatic syndrome is stressed.

Adolescent↗