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Biomedical subjects

Y Murai

Publications and source records attributed to Y Murai.

At least 199 records · Page 11Linked to original sources
PubMed1983

Hypertrophic neuropathy with diabetes mellitus.

A 52-year-old male with diabetes mellitus showed sensorimotor disturbance of symmetrical glove and stocking distribution. Electromyography demonstrated signs of denervation, and motor nerve conduction velocities could not be obtained because the muscle action potential was not evoked by the electrical stimulation of the nerves. Quantitative histologic and ultrastructual studies were performed in the sural nerve biopsy. Determination of fiber densities revealed a striking decrease of both myelinated and unmyelinated fibers and remarkable increase of the onion bulb formations. Hypertrophic changes with onion bulb formations have been observed in various clinical conditions, particularly in hereditary disorders, but uncommon in diabetic neuropathy. Our case was non-familial and may form one atypical type of diabetic neuropathy.

Diabetic Neuropathies↗
PubMed1983

Computed tomography in calcification of ligamenta flava of the cervical spine.

A case with cervical myelopathy caused by massive calcifications of ligamenta flava is presented. The round radiopaque nodules were found on conventional cervical radiography. Following examination by computed tomography, the nodules were diagnosed as calcified ligamenta flava in the cervical spine. The findings were confirmed at surgery and by histological investigations.

Aged↗
PubMed1983

Syndrome of continuous muscle-fiber activity: increased CSF GABA and effect of dantrolene.

In a patient with a syndrome of continuous muscle fiber activity, peripheral nerve block completely abolished the EMG discharges. Reduction of spontaneous discharges by epidural block and demonstration of a silent period after the H response suggested that the disorder may originate in the spinal cord or ventral roots, sparing inhibitory influences on the alpha-motoneuron to some extent. GABA (gamma-aminobutyric acid) content in CSF was remarkably increased. Therapeutically, dantrolene sodium was as effective as phenytoin or carbamazepine.

Adolescent↗
PubMed1983

[KM 2210 therapy for chronic lymphocytic leukemia].

Two previously untreated patients with chronic lymphocytic leukemia (CLL) were treated with KM 2210 50 mg/day orally for 30 and 14 days, respectively. They showed good responses: One achieved complete, the other partial, remission. Toxicity was not observed in either patient. KM 2210 was thought to be an effective drug for CLL.

Aged↗
PubMed1982

Neurophysiological effects of methyl mercury on the nervous system.

There was electrophysiological and histological evidence of axonal degeneration in sural nerves of rats with methyl mercury intoxication. In monkeys, there was no sensory nerve involvement, whereas somatosensory and visual evoked potentials showed progressive slowing of their major peaks in the course of the intoxication. Pathological changes were confined to the calcarine cortex. The possibility of sensory nerve involvement in patients with organic mercury poisoning was discussed.

Animals↗