Biomedical subjects
Publications and source records attributed to Y Monden.
A 6-month-old girl was not to have fever and stridor. Investigations revealed an abnormal lung that communicated with the esophagus and had a systemic arterial supply from the abdominal aorta. Resection of the abnormal lung was performed successfully. We have termed this disorder total lung ectoplasia. Ten patients from the literature were reviewed.
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In 42 cases of myasthenia gravis with thymoma, the tumor was removed surgically. In four of these cases, myasthenic symptoms had remitted before operation. However, in two of these four cases, myasthenic symptoms returned after operation, despite apparently total thymectomy. In two of the four cases that remitted before operation, the thymus was found to be highly involuted, without germinal centers; in another case, the thymus was found to be moderately involuted, and germinal centers were found. In the nonrelapsing cases, only the tumor itself was removed, with residual thymic tissue being left behind. The thymoma in all cases consisted of polygonal epithelial cells and lymphocytes.
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In order to quantify the lymphocyte to epithelial cell ratio (L/E ratio of the thymoma, actual counting was performed. The L/E ratio was investigated in 25 specimens of 22 cases (22 initial tumors and 3 recurrent tumors). L/E ratios ranged from 0.27 to 4.10, and the mean value was 1.93 +/- 0.21. The mean L/E ratio of histologically malignant group was lower than that of the benign group. In the three recurrent cases, L/E ratios of the recurrent tumor decreased in all cases. It was concluded that the epithelial element increases with the adva
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