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Biomedical subjects

Y Monden

Publications and source records attributed to Y Monden.

At least 253 records · Page 14Linked to original sources

[CT of thymoma].

Explore the source record for details and available documents.

Adult↗

Reoperation after transcervical thymectomy for myasthenia gravis.

Among 137 thymectomized patients with nonthymomatous myasthenia gravis (MG), six were reoperations. Thymectomy had initially been performed by the transcervical approach, but was ineffective. Extended thymectomy was then performed by median sternotomy. The reoperations revealed residual thymus (average weight, 19 gm) in all cases. Postoperative courses were favorable in three patients and unfavorable in three others. The latter had received high-dose steroid therapy before the second operation. We conclude that total thymectomy by the transcervical approach is almost impossible, and that reoperation may accelerate improvement in some cases.

Adult↗

Follow-up study of thymomas with special reference to their clinical stages.

Follow-up data were obtained for 96 cases of thymoma. The one-year survival rate was 84.3%, the three-year 77.1%, the five-year 74.1%, and the ten-year 57.1%. The five-year survival rate of total resection group was 88.9%; that of non-radically treated group was 44.4%. Clinical stages were defined: Stage I--macroscopically encapsulated and microscopically no capsular invasion; Stage II--1. macroscopic invasion into surrounding fatty tissue of mediastinal pleura, or 2. microscopic invasion into capsule; Stage III--macroscopic invasion into neighboring organ; Stage IVa--pleural or pericardial dissemination; Stage IVb--lymphogenous or hematogenous metastasis. Five-year survival rates of each clinical stage were 92.6% in Stage I, 85.7% in Stage II, 69.6% in Stage III, and 50% in Stage IV. Recurrence after total resection was found in six of 69 cases. Seven of 13 patients treated by subtotal resection survived more than five years with postoperative radiotherapy.

Adolescent↗

Primary malignant lymphoma of the trachea. Report of a case successfully treated by primary end-to-end anastomosis after circumferential resection of the trachea.

A 67-year-old Japanese man with exertional dyspnea was found by laminagraphy to have tracheal obstruction. The stricture was localized at the cervical and mediastinal trachea and was 5.0 cm long on an x-ray film. Eight tracheal rings were successfully resected and the ends of the trachea were anastomosed. The lumen of the removed trachea was narrowed by intramural and intraluminal polypoid growth originating from the tracheal wall. Histologically, the tumor was diagnosed as a mixed type of malignant lymphoma. The patient had serum hepatitis postoperatively, but now he is living normally without any difficulty in respiration. No signs of recurrence have been seen in the 5 years, 4 months since the operation. From this experience, the rarity and the possibility of curative operation of this tumor are discussed.

Aged↗

Normal anatomy of thymus and anterior mediastinum by pneumomediastinography.

Normal radiographic appearances of the thymus and anterior and superior mediastinum based on 34 pneumomediastinograms performed on myasthenia gravis patients are discussed. Knowledge of (1) end-on shadow of major vessels in the mediastinum, (2) topographic relation between major vessels and bilateral lobes of the thymus, (3) variable shape, size, and uneven outline of the normal thymus, and (4) irregularly distributed mediastinal fat, helps make more precise radiographic interpretation in this region.

Adipose Tissue↗