Psoriasiform dermatitis in a cachectic man. Acrokeratosis paraneoplastica (Bazex' syndrome).
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Biomedical subjects
Publications and source records attributed to Y Lynfield.
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Tinea capitis, a disease of children, occurs throughout the United States. We studied 144 clinically diagnosed cases of tinea capitis within a 12-month period. Ninety-six of them had positive cultures; Trichophyton tonsurans grew in 89% and Microsporum organisms in 11%. Ninety-five (99%) of the patients with positive cultures were black, and one (1%) was hispanic. The peak incidence was in the 4-to-5-year age group. Boys and girls were equally affected. Sixty percent of the 96 culture-proved cases were noninflammatory, and 40% were inflammatory (kerions). In four patients, the initial clinical manifestations were severe diffuse seborrhealike scales and crusting of the scalp with minimal alopecia. Mycologic and clinical cure were obtained by a mean of 4.7 weeks of griseofulvin therapy. Neither systemic erythromycin, topical antifungal agents, nor systemic prednisone resulted in earlier eradication. However, prednisone caused the inflammation of the kerions to subside dramatically.
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A diabetic patient had delayed local cutaneous allergic reactions to insulin. We describe his lesion, biopsy findings, and treatment. Allergic reactions to insulin may be immediate local or systemic, which are lgE-mediated. Recommended management of local reactions is to use a single-peak pork insulin of the insulin zinc suspension series. Progressive immediate local reactions may herald the onset of systemic reactions. Hospitalization and desensitization to insulin may be required for systemic allergic reactions to insulin.
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Fifty-nine patients with bilateral psoriatic lesions were subjects in a double-blind paired comparison of halcinonide cream and fluocinonide cream. They applied the corticosteroid creams twice a day for 14 days without occlusive dressings. Objective and subjective assessment of response to therapy was made four or five days, one week, and two weeks after starting treatment. The results were analyzed by statistical methods. At the second visit (day 4 or 5), there was little difference between the two compounds, but at visits three and four, reduction of inflammation was significantly better with halcinonide than with fluocinonide.
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