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Biomedical subjects

Y Jiang

Publications and source records attributed to Y Jiang.

At least 685 records · Page 38Linked to original sources

[Analgesic and sedative effects of the Chinese drug rhizoma Paridis].

The analgesic and sedative actions of Chinese drug Rhizoma Paridis are reported. All of the 6 experimented species and varieties in common use are obviously effective. Among them Paris polyphylla var. chinensis, P. polyphylla var. yunnanensis are stronger in analgesic action. Sedative action of P. fargesii, P. polyphylla var. chinensis, P. thibetica is also strong. In addition, pariphyllin A and gracillin were also used in the experiment.

Analgesics↗

[Study of logistic curve fitting for primary liver cancer death rate in Chengdu].

Logistic curve was used for fitting primary liver cancer (PLC) age-specific death rate in Chengdu. The results showed that the age-specific death rate from 1981 to 1986 in Chengdu (population about 4,000,000) was satisfactorily fitted by logistic curve in male, female and total (P less than 0.01). The R2s were 0.9885, 0.9912 and 0.9974, respectively. Velocity analysis of death rate showed that the increasing peak was in the group of age 40-60 for male and 50-65 for female. Male's velocity and slope of death rate were higher and steeper than female's. These results are consistent with the feature of logistic curve and parameters obtained from logistic curve fitting in this study. The age-specific death rate by sex for every year from 1981 to 1986 was fitted very well (P less than 0.01). R2s for male and female were 0.9415 +/- 0.044 and 0.9056 +/- 0.048, respectively.

Age Factors↗

Studies on fertility control-the formation and antifertility effect of polyvinyl-pyrolidone-gossypol complex.

In this study, PVP-gossypol complexes with different molecular weights and compositions were synthesized. UV and NMR spectra revealed the presence of hydrogen bonds in these complexes. The dissolution rates of various PVP-gossypol complexes in water at 37 degrees C were determined. The results showed that the presence of PVP in the complex enhanced the dissolution rate of gossypol in water greatly. In addition, the in vitro spermicidal activity on human semen, antifertility effect on male rats, and the toxic reaction of male mice by taking large dosage were preliminarily studied. The experimental results indicated that the PVP-gossypol complexes not only possessed the similar antifertility effect and acute toxicity to male mice as gossypol-acetic acid, but also reduced the irreversibility of the fertility as well. Thus, certain species of PVP-gossypol complex may have potential as new and better male oral contraceptive with recoverability in fertility.

Animals↗