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Biomedical subjects

Y Itzchak

Publications and source records attributed to Y Itzchak.

At least 73 records · Page 4Linked to original sources

Sonography of periventricular leukomalacia.

Periventricular leukomalacia (PVL) is a pathological entity characterized by ischemic changes in areas adjacent to the external angles of the lateral ventricles. It is associated with serious neurodevelopmental sequelae, especially spastic diplegia. With the increased use of ultrasound in the Neonatal Intensive Care Unit, changes consistent with PVL are being noted. Hemorrhagic and nonhemorrhagic forms of this condition exist, both of which may appear sonographically as increased periventricular echogenicity. Two cases of PVL are described; one of them was associated with ventricular dilatation and intraventricular bleeding and the other with a small subependymal hemorrhage. The pathological and clinical features, methods of in vivo diagnosis, and the role of ultrasound in the evaluation of PVL are discussed.

Brain Diseases↗

Posterior mediastinal accessory thymus.

A rare case of accessory ectopic thymus in the right upper posterior mediastinum in a 40-day-old infant is described. The clinical presentation was that of tracheal obstruction. The compression and displacement of the trachea and the identification of the mass was enabled thanks to the high KV filtration technique. The mass was further identified by ultrasonography. Surgical removal of the accessory thymus relieved the tracheal obstruction.

Humans↗

The pylorus in infancy: overall sonographic assessment.

A prospective ultrasonic evaluation of the pylorus was performed in two groups of infants, a control group and a group of infants clinically suspected of having hypertrophic pyloric stenosis (HPS). The mean pyloric length in the hypertrophied condition was 84% longer than the mean length in the normal. The mean and standard deviation (sd) for the transverse diameter and pyloric wall thickness in the normals were 7.45 +/- 2.2 mm and 2.3 +/- 0.7 mm respectively, while the corresponding measurements for the mean and sd in HPS were 13.4 +/- 1.6 mm and 4.5 +/- 0.9 mm. In most of the HPS cases the known morphological changes of the antro-pyloric region such as: impingement on the fluid filled antrum, pre-pyloric antral thickening, extension of fluid into the proximal portion of the pyloric canal and the angle formed between antral peristaltic wave and pyloric mass, were observed. Detection of these changes furnished further criteria for highly accurate diagnosis of HPS even of borderline cases.

Female↗

Echinococcus of the urinary tract: radiologic findings.

Echinococcal involvement of the urinary tract is extremely rare. We present 11 such cases, 10 with renal and 1 with bladder involvement. Clinical and laboratory findings were nonspecific. Calcification was present in all but 1 case. The excretory urogram and retrograde pyelogram demonstrated parenchymal soft-tissue masses causing pressure on and dilatation of the collecting system. Angiography in 3 cases showed the masses to be avascular. The ultrasound findings of a multicystic lesion with mixed echogenicity were typical of echinococcal cysts, while a CT scan in 1 patient showed a cyst with densely calcified border. The combined findings of these different modalities aid greatly in establishing the correct diagnosis.

Adult↗

Hyperechoic foci in the gallbladder wall as a sign of microabscess formation or diverticula.

Abdominal sonography in 7 patients with acute biliary disease revealed focal echo collections within the wall of the gallbladder in addition to cholelithiasis and diffuse mural thickening. A prospective study was conducted, comparing in vivo and in vitro sonography of the gallbladder with histopathological findings. In 3 patients, microscopy of the hyperchoic tissue showed microabscesses. In 4, intramural diverticula containing inspissated bile, small stones, or cholesterol crystals were seen. The authors caution that hyperchoic foci within the wall of the gallbladder may indicate intrinsic disease separate from cholelithiasis or cholecystitis.

Abscess↗

Torsion of the ovary: sonographic features.

The sonographic findings in 19 cases of surgically proven torsion of the ovary are described. In all cases the affected ovary was markedly enlarged; in 32% of cases a small amount of fluid was detected in the cul-de-sac. More significant in terms of specificity was the demonstration in 14 (74%) of the 19 cases of small cystic structures scattered around the periphery of the organ. Sonographic demonstration of these structures, presumably prominent follicles, can suggest the preoperative diagnosis of ovarian torsion.

Adult↗

Preoperative ultrasonic measurements of the thickness of cutaneous malignant melanoma.

Preoperative measurements of the thicknesses of pigmented skin lesions by high-resolution sonography have been studied. Fourteen nevi and 15 malignant melanomas were examined and their thicknesses compared with those measured on both paraffin and frozen sections. Linear regression coefficients of r2 = 9.22 and r2 = 9.23, respectively, were found. This good correlation suggests that sonography may be of value as a guide in predicting prognosis and in determining the proper course of treatment for patients with malignant melanoma.

Frozen Sections↗

Rhabdomyosarcoma of the cord: ultrasonic evaluation.

A rare case of paratesticular rhabdomyosarcoma in a young adult is described, emphasizing the role of ultrasonic preoperative examination in evaluating the consistency and extension of the scrotal mass for surgical management.

Adult↗

Sonographic differentiation of extra- and intrahepatic masses.

The sonographic features in the evaluation and differentiation of extra- and intrahepatic masses were assessed in two groups of patients. These signs included discontinuity of the liver capsule, internal invagination or external bulging of the liver capsule, formation of a retroperitoneal fat wedge, displacement of the intrahepatic portal vessels or hepatic veins, shift of the inferior vena cava, and displacement of the right kidney. Evaluation of the results in 25 patients in whom the mass was intrahepatic and in 33 with an extrahepatic mass indicates that internal invagination of liver capsule (81.8%), its discontinuity (33.3%), formation of triangular fat wedge (75.7%), shift of the inferior vena cava anteromedially (36.3%), and anterior displacement of right kidney (28.1%) are the signs most frequently observed in extrahepatic masses. The characteristic features of the intrahepatic masses were displacement of hepatic vascular radicles (84%), external bulging of the liver capsule (56%), and posterior shift of the inferior vena cava (32%). The evaluation of masses in the right upper abdomen according to these criteria gives an accurate definition of their anatomic origin. However, masses exceeding 10 cm in diameter may present diagnostic problems.

Adenocarcinoma↗

Ultrasound and computed tomography in the diagnosis and drainage of abscesses and other fluid collections.

The indications, technique and results of percutaneous drainage in 20 patients with abscesses and other fluid collections are presented. Special emphasis is placed on the complementary use of ultrasound and computed tomography and the relative indications for the use of each. Of the 20 patients, 5 had hepatic abscesses, 7 had subphrenic or subhepatic abscesses, 3 had pancreatic pseudocysts and the remaining 5 had loculated fluid collections in either the abdomen or chest.

Abdomen↗