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Y Hata

Publications and source records attributed to Y Hata.

At least 487 records · Page 27Linked to original sources
PubMed1981

Usefulness of 24-hour recordings of electrocardiogram for the diagnosis and treatment of arrhythmias with special reference to the determination of indication of artificial cardiac pacing.

Twenty-four-hour recordings of electrocardiogram (ECG) were obtained from 1528 subjects. Sick sinus syndrome (SSS) was observed in 34 and advanced or complete AV block (CAVB) in 13 subjects. During the period studied 21 patients had died, who showed complicated ventricular premature contractions in 9 (multiform 6, short run 2, repetitive 2). Seventy-three patients with artificial cardiac pacing who were admitted at three different institutions were analyzed. The discrepancy of degree of block was observed between His bundle electrocardiographic findings and 24-hour ECG recordings. In 15 patients there was no correlation between sinus node recovery time following overdrive suppression and pauses following the termination of tachycardia (r = 0.0896, N. S.). In 49 normal subjects 24-hour heart rate ranged from a high of 170 to a low of 36 beats/min. Longest R-R interval ranged from 2.08 to 0.86 sec (mean 1.25 +/- 0.22 sec). The critical level of longest R-R interval to differentiate between normal group and groups with SSS or CAVB was about 1.6 sec. Above results suggest that Holter monitoring permits a precise diagnosis of arrhythmias and that both HBE and Holter monitoring should be used for the determination of pacemaker implantation especially in those with syncope or dizziness but without evidence of marked bradycardia.

Adolescent↗
PubMed1980

Accessory scrotum.

A case of rare accessory scrotum has been presented. Previous literature is reviewed and the cause has been discussed. Surgery was performed successfully.

Child↗
PubMed1980

Cholesteryl ester-rich lipid inclusions from human aortic fatty streak and fibrous lesions of atherosclerosis. II. Physical properties of swelling, resiliency and lyotropy as liquid crystal.

The physical properties of the lipids accumulating as spherical inclusions in human atherosclerotic lesions were explored both in vivo and in vitro conditions. They were mostly anisotropic within the cytoplasma of cells and in an average diameter of 1.96 mu. When suspended in hydrophilic media, say of physiological saline solution, in 4 hours they swelled 2.4 times in volume and changed into isotropic form. They were resilient and deformable in three dimensional configuration, and lyotropic in polar media. When dried they underwent a phase shifting from liquid crystal to true solid crystal. These physical properties of lipid inclusions gained in a new significance for their role in metabolic deterioration of intima cells, rupture and necrosis of foam cells, and destruction of the intimal and medial architectures, which set on mesenchymal reactions leading eventually to thickening and hardening of the arteries.

Adult↗
PubMed1980

Inhibition of PG biosynthesis as the maintenance mechanism of pregnancy of hCG.

In general, when the hCG values in the serum and urine reached their first peak, the PGF2 alpha and PGF2 alpha-MUM levels dropped. The hCG fell rapidly in inverse proportion to PGF2 alpha. During late pregnancy, hCG levels increased slightly and PGF2 alpha reached a low level again. From these observations, it can be stated that both PGF2 alpha and hCG played important physiologic roles in the maintenance of pregnancy. Normal pregnancy depends on this special antagonism. This anatagonism seems to be maintained by proper concentration of both hCG and PGF2 alpha. When this antagonism is disturbed during pregnancy as described above, the tendency toward decrease of hCG and increase of PGF2 alpha manifests and hence threatened abortion or actual abortion may result.

Abortion, Spontaneous↗
PubMed1979

Low resolution crystal structure of lipase from Geotrichum candidum (ATCC34614).

Lipase from Geotrichum candidum (ATCC34614) is a glycerol ester hydrolase which has a molecular weight of 55,000 with about 7% carbohydrate, displaying a high affinity for triolein. The enzyme was crystallized from more than 2% protein solution without using any salt or organic solvent. The crystals were cross-linked by soaking in 0.37% glutaraldehyde solution (0.1 M acetate buffer solution, pH 5.6). The structure was determined by X-ray diffraction using the isomorphous replacement technique. Two heavy-atom derivatives [K2PtCl4 and UO2(CH3COO)2] were obtained by the soaking method. The electron density map calculated at 5 A resolution clearly showed the molecular boundary. A balsa wood model was made on the basis of the 6 A electron density map. The molecular has an ellipsoidal shape with dimensions of 70 A X 50 A X 50 A. Several columns of density corresponding to alpha-helix and a few clefts were found in the molecule. The active site is presumably located in the vicinity of one of the Pt sites in the Pt-derivative crystal, judging from the inactivation of the enzyme by K2PtCl4.

Cross-Linking Reagents↗
PubMed1979

Structure of bonito heart ferricytochrome c and some remarks on molecular interaction in its crystalline state.

The structure analysis of bonito heart ferricytochrome c was carried out at 2.8 A resolution by X-ray diffraction. The overall features of the molecule are virtually identical with those of bonito ferrocytochromes c and other cytochromes c. In the present work, the modes of molecular packing among cytochromes c were also compared by means of intermolecular distance maps. Some differences in the structures of ferro- and ferricytochrome c may exist on the surface of the molecules.

Amino Acids↗
PubMed1979

[Hepatic tumors in childhood (author's transl)].

The results of Treatment of Liver malignant primary tumors are analyzed. 16 Tumors have been treated in 15 years. The best method appeared to be radical Hepatic resection. The post operative level of A.F.P. is the first sign of Tumor recurrence and permits an Intensive Chemotherapy.

Carcinoma, Hepatocellular↗
PubMed1978

Thyroid cancer in childhood.

Thyroid cancer in childhood is a relatively rare condition. Often it shows biological characteristics different from those seen in adults. Based upon 10 cases in our clinic and 57 cases collected from the Japanese literatures, clinical features, pathology, treatment and prognosis of thyroid cancer in childhood are discussed. Pathogenesis is most likely to be related to hormonal changes during adolescence and previous radiation of the neck region. Cervical lymph nodes swelling was the chief complaint in 84.6 per cent of the cases. On the other hand, pulmonary metastases were recognized in the early stages in 33.5 per cent of the cases. Radical excision of the tumor with modified radical neck dissection is the treatment most frequently employed even in the presence of lung metastases. However, hypoparathyroidism and recurrent nerve injuries should be avoided at all cost in view of long life expectancy and the difficulty in treating them satisfactorily. Prognosis could be as good for children as it is for adults except in cases with early lung metastases.

Adenocarcinoma↗
PubMed1978

A xerographic method for the quantitative assessment of atherosclerotic lesions.

A new method has been developed for the quantitative assessment of atherosclerotic lesions, in which a conventional xerox machine is the sole equipment used. As an example, the aorta from a cholesterol-fed rabbit was removed in toto, opened longitudinally along its anterior margin, flattened in a transparent polypropylene bag and then xeroxed. The outlines of the atherosclerotic lesions were traced on translucent graph paper ruled into 1 mm squares. The squares within those outlines were counted and expressed as a percentage of the whole surface. This xerographic method is rapid and reproducible and is achieved without changing the magnification; it gives comparable or better results than other staining methods. As the aortic specimen is undamaged by fixation or staining, the specimen can be used for subsequent morphological or biochemical studies. Thus, the degree of surface involvement can be correlated with other morphological or biochemical changes in the same arterial samples.

Animals↗