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Biomedical subjects

Y Copelovici

Publications and source records attributed to Y Copelovici.

61 records · Page 4Linked to original sources
PubMedDate not supplied

[A seroprevalence study of the hepatitis C virus among multiply transfused patients].

A study was conducted on 61 polytransfused patients, 24 patients submitted to long lasting parenteral treatments, 116 blood donors and 132 controls. Immuno-enzymatic tests were used for detection of antibodies against hepatitis C virus (HCV). They were found in 56 (91.8%) out of the 61 polytransfused patients, in 5 (4.3%) of the donors, in 5 (20.8%) of the patients with multiple treatments and in 5 (3.7%) controls. The VHB markers were detected at variable rates in all investigated groups. The high rate of seropositivity indicates that hepatitis C is becoming an important public health problem in Romania.

Adult↗
PubMedDate not supplied

Immunological disorders of increased severity in children with AIDS associated with hepatitis B and C infections.

Two groups of children were set up: children infected with HIV and hepatitis viruses and children infected with HIV, but not with hepatitis viruses, too. The immunological aspects investigated referred to the Ig serum value, the absolute number of T CD4 lymphocytes and the T CD4/T CD8 ratio. The subjects of the first group (in whom hepatitis markers were present) displayed increased IgA and IgM values at a higher rate than those of the second group (54.87% against 32%, 83.3% against 53%), as well as a lowering below 300/ml of the number of T CD4 lymphocytes (50% against 29.4%). On the other hand, increased IgG levels and values below 0.8 of the T CD4/T CD8 ratio were found at similar rates in the two groups of children (77.4% against 80% and 70.5% against 70% respectively). By means of the data obtained, the authors try to point out one of the ways by which hepatitis viruses, considered as a potential cofactor in the AIDS development, contribute to the course of this disease, namely by intensifying the immunological disorders.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

Data on the efficiency of specific antimumps immunoglobulins in the prevention of mumps and of its complications.

Administration of specific antimumps immunoglobulins(Ig) to mumps contacts in various children communities conferred protection only when performed early after the outbreak of the epidemic and if the proportion of previous mumps cases did not surpass 8% of the total number of children. Application of specific Ig to mumps patients within the first 5 days after onset prevented the appearance of secondary determinations and/or complications and reduced the duration of the disease and of the hospitalization period. The efficiency of standard gamma-globulins was very limited.

Child↗
PubMedDate not supplied

[Seroprevalence of hepatitis C virus among the multiply transfused].

A study was conducted on 61 polytransfused patients, 24 patients submitted to long lasting parenteral treatments, 116 blood donors and 132 controls. Immuno-enzymatic tests were used for detection of antibodies against hepatitis C virus (HCV). They were found in 56 (91.8%) out of the 61 polytransfused patients, in 5 (4.3%) of the donors, in 5 (20.8%) of the patients with multiple treatments and in 5 (3.7%) controls. The VHB markers were detected at variable rates in all investigated groups. The high rate of seropositivity indicates that hepatitis C is becoming an important public health problem in Romania.

Adult↗