Biomedical subjects

Y Akine

Publications and source records attributed to Y Akine.

75 records · Page 5Linked to original sources

PubMedDate not supplied

Ir-192 brachytherapy by an afterloading technique: initial experience at the National Cancer Center Hospital, Tokyo.

Twenty-nine patients with various tumors treated by 192Ir brachytherapy at the National Cancer Center Hospital from 1977 to 1984 were reviewed. Of 10 patients with carcinoma of the extrahepatic bile duct, three with carcinoma of the urinary bladder, and three others with various tumors, none showed locally controlled disease. Two of six patients with recurrent brain tumor, three of five with skin tumor and two with carcinoma of the female genital tract showed locally controlled disease. Although the effectiveness of this mode of treatment needs to be more clearly demonstrated, it is easily applied to clinical practice and is at least as effective as radium 262 implantation.

Adult↗

PubMedDate not supplied

Suppression of bony growth of the orbit after radiotherapy for retinoblastoma.

Suppression of the growth of orbit and skull in 13 retinoblastoma patients treated by radiotherapy was investigated. The age of patients at the time of treatment ranged from 1 month to 6 years and 11 months. They were examined after three to 18 years. Suppression of the growth in involved areas and other parts of the skull within the beam of radiation were estimated by inspection, X-ray findings, and X-CT examinations. The involved orbit received more than 32 Gy, and the suppression of bone growth was prominent. At the opposite temporal bone, suppression of growth was prominent in eight cases out of 11, in these cases, the radiation dose was at least 14 Gy. Two cases, in whom the radiation dose was less than 12.6 Gy, have not shown any suppression of bony growth. Results were also obtained for a nominal single dose (ret). In all cases of more than 1,000 ret, suppression was prominent, but at less than 1,000 ret, four out of nine cases, and at less than 600 ret, two out of four cases showed suppression of bony growth. If the safety dose to avoid the suppression of bony growth is 400 ret, this is equivalent to three times the radiation dose of 200 cGy. In conclusion, the suppression of bony growth of the orbit and temporal area of the skull of young patients is caused by very small doses of radiation.

Bone Development↗

PubMedDate not supplied

Treatment of metastatic gastric cancer by combined radiation and hyperthermia (report of two cases).

Two patients with metastatic carcinoma of the stomach on the abdominal wall were treated by radiotherapy using cobalt-60 gamma-ray or megavoltage electrons combined with hyperthermia induced with a Thermotron (8 MHz). The total dosage was 44 Gy fractionated into 11 doses (twice a week), by cobalt-60 gamma-ray and 10 hyperthermia treatments for patient 1, and 32 Gy fractionated into eight doses (twice a week) given by megavoltage electrons and five hyperthermia treatments for patient 2. In patient 1, the shrinkage of the tumor was more than 50%. No tumor cells were observed histologically at the end of treatment. In patient 2, the tumors completely disappeared. These results encourage us in the use of radiotherapy combined with hyperthermia for rather radioresistant adenocarcinoma.

Abdominal Muscles↗