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Biomedical subjects

W Wolf

Publications and source records attributed to W Wolf.

At least 181 records · Page 10Linked to original sources
PubMed1976

Adverse reactions to radiopharmaceuticals.

This review covers the side effects and adverse reactions to radiopharmaceuticals that were reported in the literature over the past 25 years. The information published prior to 1970 is sporadic, but due to the increased utilization of nuclear medicine procedures and the recognition that radiopharmaceuticals may have pharmacologic side effects, a registry has existed since 1971 to tabulate information on such effects. This survey is medical, rather than pharmaceutical in emphasis and so the adverse reactions are classified according to the target-organ systems involved rather than according to the specific radionuclides or to pharmaceuticals. If any of the radiopharmaceuticals of present or past use are not mentioned in this review, it is because no reports on their side effects were retrived by us. Hopefully, the organized registry system suggested by the Society of Nuclear Medicine (SNM) will enable a more complete recording of side effects from radiopharmaceuticals in the future.

Bone Marrow↗
PubMed1975

[Hemoblastosis and genital manifestations (author's transl)].

The course of the disease in a woman with a malignant lymphoma is described. The primary disease was recognized through an early involvement of the uterus which led to hemorrhages. While observations of this kind are relatively seldom communicated, examination of the literature showed that involvement of the genitals is to be reckoned with relatively frequently with hemoblastoses in the advanced stages. Regular gynecological investigations are therefore essential for women with hemoblastoses.

Breast Neoplasms↗
PubMed1975

Are all gallium citrate preparations the same?

Recent studies on brain imaging using 67Ga citrate from three different manufacturers revealed some clinical differences. Using chromatographic techniques, it was found that 67Ga citrate supplied by vendor A clearly differed from those of vendors B and C in mobility. When citrate was added to material of vendor B to bring the final concentration to 25 mg/ml, the chromatographic mobility increased dramatically. Addition of benzyl alcohol had no effect. The mechanisms involved in causing these chromatographic changes are not clear; however, the in vitro variations noted indicate a difference in chemistry which may ultimately affect the distribution and localization of the radiopharmaceutical.

Chromatography, Gel↗
PubMed1975

[On the question of recurrent carcinoma in-situ of the uterine cervix].

Among 280 patients with carcinoma in-situ of the uterine cervix treated from 1961 to 1970, a review of the histology revealed 50 patients in which the carcinoma in-situ had been removed with certainty by conization. None of these patients was found to have had a recurrence. In the literature, 13 observations of a recurrence of carcinoma in-situ after complete removal by conization were located among 3, 129 cases. It is concluded that true recurrence after complete removal of carcinoma in-situ by conization is rare and that conization is adequate treatment for carcinoma in-situ for patients who attend regular follow-up examinations.

Adult↗
PubMed1975

Hospital radiopharmacy training program.

Training of radiopharmacists, including self-study and a hospital short-term course, is discussed. A systematic approach for self-study is suggested. The 30-day hospital training program described includes both didactic material and on-the-job experience.

Curriculum↗