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Biomedical subjects

W Wohlrab

Publications and source records attributed to W Wohlrab.

At least 91 records · Page 5Linked to original sources
PubMed1984

[Epidermal reaction kinetics following benzol contact].

With benzene as model substance the reaction of the epidermis to different concentrations of harmful substances is examined in animal experiments. This shows that with biometrically unobtrusive results dependent on benzene concentration and penetration time, distinct changes take place in the function of the epidermis cells. These results are essential for the pathogenesis and prophylaxis of skin damaged by exposure to harmful substances at industrially permissible concentrations of noxa.

Administration, Topical↗
PubMed1982

[Reaction of skin and various cell systems after contact with sodium hypochlorite as a model substance (author's transl)].

The efficacy of an externally applied substance is possible by the combination of various experimental methods for investigation of the reaction of the skin and other cell systems. After different contact time of skin or epidermal cells with NaOCl solution under in vivo and in vitro conditions, an influence on the processes of epidermal proliferation, development and differentiation was not provable. On the other hand alterations in other cell systems could be observed. In lymphocytes the content of incorporated 3H-thymidine after in vitro cultivation remained unchanged, however, the possibility of stimulation with PHA was decreased. After external skin contact a comparative analysis of different metabolic processes for interpretation of substance efficacy is necessary.

Animals↗