[Follow-up examinations of lung function in patients with shock lung].
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Biomedical subjects
Publications and source records attributed to W Wenz.
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Preliminary results concerning the occlusion of experimental atrial-septal defects (ASDII) of the secundum type are reported. An occlusion element was inserted transvenously and its passage across the atrial-septal defect was controlled by open-heart surgery in dogs. Subsequently, the defect was occluded using a single-piece element. In all 5 surgical experiments the occlusion was possible without dislocation or embolism of the element during an atrial stimulation of the heart for more than 1 hour. In additional experiments without open-heart surgery, atrial-septal defects were produced in 7 dogs by transseptal punction and perforation under X-ray control. The atrial-septal defects could be closed for a short time in 2 dogs. In 1 of the 2 dogs the element embolized into the right pulmonary artery, and in the other into the abdominal aorta. Transvenous occlusion of experimental atrial-septal defects is possible, but more experimental work is necessary with respect to the technical problems.
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Catheters for cardiovascular and other angiographic investigations can be resterilized by ethyl-oxide. The procedure of sterilisation has to be controled permanently. Reapplicability of catheters has become quite common because of the high price of new catheters. In spite of optimal resterilisation and permanent controll some patients still get fever attacks, because endotoxins cannot be eliminated by this method.
Angiographic findings in blunt abdominal trauma are reviewed. 693 posttraumatic angiograms were performed at the University of Freiburg from 1971-1980. 24% of these patients suffered from blunt abdominal trauma. It could be shown that recently ultrasonography and computerized tomography have replace angiography as screening method. Remaining indications for angiography are primary vascular lesions, uncertain findings of US-and/or CT-examination and documentation of hemorrhage with the possibility of therapeutic intervention.
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Sonography and abdominal survey are the basic image-producing examinations in obstructive jaundice. Excretory cholegraphy fails when the serum bilirubin level is more than 2 mg%. The method of choice for direct visualization of the biliary tract is to try an endoscopic retrograde contrast injection. If this fails, percutaneous transhepatic cholegraphy may be offered with more than 90% accuracy. This simple technique is easily changed into percutaneous biliary drainage. Our experience with more than 120 cases is reported.
The occasion of transferring old archives of angiograms done between 1935 and 1940 to our present department led to the review of techniques and problems of angiography in these days; including a review of contrast agents, initial possibilities for series arteriography, puncture methods and catheter technique.
Any pathological damage occurring in a bone will produce either an osteolytic or osteosclerotic lesion which can be seen in the macroscopic specimen as well as in the roentgenogram. Various bone lesions may lead to local destructions of the bone. An osteoma or osteoplastic osteosarcoma produces an osteosclerotic lesion showing a dense mass in the roentgenogram; a chondroblastoma or an osteoclastoma, on the other had, induces an osteolytic focal lesion. This paper presents examples of different osteolytic lesions of the humerus. An osteolytic lesion seen in the roentgenogram may be either produced by an underlying non-ossifying fibroma of the bone, by fibrous dysplasia, osteomyelitis or Ewing's sarcoma. Differential diagnostic considerations based on the radiological picture include eosinophilic bone granuloma, juvenile or aneurysmal bone cyst, multiple myeloma or bone metastases. Serious differential diagnostic problems may be involved in case of osteolytic lesions occurring in the humerus. Cases of this type involving complications have been reported and include the presence of an teleangiectatic osteosarcoma as well as that of a hemangiosarcoma of the bone.
Presentation of different kinds in the course of tuberculosis of the lung. Comparison of pathologic-anatomical findings and radiology of an active, exudative, cavernous, cirrhotic, and miliary tuberculosis. Discussion of the concept of activity from different points of views: clinical, radiological, and histological.
Gastrointestinal symptoms frequently occur in patients with hypogammaglobulinemia of the late-onset idiopathic type, but intestinal nodular lymphatic hyperplasia (INLH) is rarely found. The characteristic radiological findings of the small bowel are reported in two patients with this well defined syndrome. The aspects of the radiological differential diagnosis of multiple small nodular filling defects of the intestine are discussed.
Since the introduction of hyposensitization more than 60 years ago as a therapeutic principle in allergic diseases the method has brought good success especially in atopic sensitizations. Pollen, domestic dust and insect allergy are generally accepted indications. The chances in these types of allergy are rather good, especially when the following points have been taken into consideration: A correct indication by subtile investigation, the best choice of allergens and optinal intervalls of applications, the sufficient duration of treatment, a reasonable high final dosis and avoidance of contraindications. Improvements in the success of this therapy as well as facilitation of the practical performance (e.g. by introduction of new allergen preparations) can be expected in the next future by intensified basic immunologic research inclose connexion with clinical practice.
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Tumorous lesions of the liver were diagnosed by means of angiography, sonography and laparoscopy in six patients on oral contraceptives for a long time. These lesions were identified as liver cell adenoma (1), focal nodular hyperplasia (4) and cavernous hemangioma (1). The relationship between oral contraceptives and liver disorders is well-known. All cases of focal nodular hyperplasia show vascular alterations which may be important in the discussion of oral contraceptives being responsible. In contrast to liver cell adenoma and hemangioma, focal nodular hyperplasia may be considered as a nodular reparative regeneration of the parenchyma following focal parenchymal necrosis due to segmental vascular occlusion (i. e. thrombosis or fibrotic intimal obliteration). This lesions can therefore not be defined as a true neoplasm. The clinical findings are uncharacteristic, whereas selective hepatic artery angiography, shows typical features that distinguish liver cell adenoma from focal nodular hyperplasia. Regular medical examinations are recommended for women on continuous oral contraceptives for more than five years, because this group of patients is threatened by serious sequelae including intrahepatic and abdominal hemorrhage.
UNLABELLED: Report on initial clinical experience with a new form of tomography with fluoroscopy, called 'tomoscopy'. PRINCIPLE: Several grid controlled x-ray tubes firmly mounted (stationary) in circular fashion -- with the foci in equidistance -- are fired in sequential fashion for a short exposure, which creates the impression of tube movement mandatory in conventional tomography, by this sequential firing of several tubes (in 1/50 second total), the mechanical tube motion of conventional tomography can be avoided. In the image intensifier, there is synchronous electromagnetic deflection of the image between input- and output screen; and a tomographic image can be seen at the output screen. This can also be recorded on camera. This new technique allows quick fluoroscopic determination of the ideal 'cut' and thus provides efficient tomography without slowing down the ongoing examination; and it is a useful addition to modern radiographic equipment with image intensification, especially when used with contrast material. Its full future impact on diagnostic radiology can yet not be estimated.
Fistulas between the biliary and gastrointestinal tract complicate 12% of cases with cholecystitis. Communications of the biliary tract occur with decreasing frequency into the duodenum, colon and stomach. Clinical symptoms of cholecysto-colonic fistulas are chills and temperature elevation indicating ascending cholangitis. As bile acids bypass the small intestine, diminished fat absorption results. The unusual amount of bile acids in the colon delays water absorption, causing bile acid diarrhea. A pneumocholangiogram is seen in only 50% of the cases. Barium enema will visualize the fistula most often.