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Biomedical subjects

W Wenz

Publications and source records attributed to W Wenz.

At least 73 records · Page 4Linked to original sources

[Computerized tomography in thoracic trauma].

Chest CT scans were obtained in 86 patients suffering from serious blunt or penetrating chest trauma. The finding of mediastinal widening was by far the most common CT indication. CT proved to be a more sensitive method for detection of parenchymal lung lesions and occult pneumothorax than bedside radiographs. CT contributed substantially in differentiation of lung abscess and empyema, exclusion of mediastinal pathology and spinal injuries. Aortography is still indicated, even when CT findings are normal if aortic laceration is clinically suspected. Despite all of the technical problems combined with CT examinations in the critically ill patient, we consider CT a valuable diagnostic tool for certain problems in the traumatized patient.

Aortic Dissection↗

Leiomyoma of the bladder.

A case of leiomyoma of the bladder in a 37-year-old man is described. Clinical features and findings on excretory urography resembled a malignant tumor of the small pelvis. Ultrasound, computed tomography, and angiography nevertheless made the correct preoperative diagnosis. Special emphasis is given to the differentiation between benign and malignant smooth muscle neoplasms.

Adult↗

[Experience with ketotifen in respiratory tract diseases].

In 2 clinical studies we tested the efficacy of ketotifen in allergic rhinitis and allergic bronchial asthma. Ketotifen was demonstrated to have a convincing effect not only upon the typical inhalation allergens, such as pollen, house dust mite or animal hair, but also upon allergens ingested via the gastrointestinal tract (food). As even long-term administration has thus far not shown toxic side-effects, ketotifen, based on appropriate indication, can already in childhood be successfully applied.

Asthma↗

[Results of hyposensitization with bee and wasp venom].

The immunotherapy with purified bee and wasp venom is indicated for patients with severe general reactions after insect stings, positive prick test and positive RAST. One hundred seventy four persons were treated for three years with bee venom (SSW Dresden) and 34 patients with wasp venom (Reless). Challenge by a stinging bee after treatment proved in 90 per cent complete protection. There were no general reactions during hyposensitization with wasp venom, but in 46 per cent occurred general reactions during immunotherapy with bee venom. Therefore rush desensitization should be performed in indoor patients till a top dose of 100 micrograms/ml is reached. Booster injections can be given to outdoor patients. All individuals with systemic reactions after insect stings have to get an emergency treatment kit and must be familiar with its application.

Bee Venoms↗

Relapsing pancreatitis associated with duodenal wall cysts. Diagnostic approach and treatment.

A case of enterogenous cysts of the duodenum in a 44-yr-old man complicated by duodenal obstruction and relapsing pancreatitis is presented. The cystic duodenal lesions were visualized by endoscopic retrograde cholangiopancreatography and for the first time by computed tomography and abdominal sonography. Thus, the diagnosis was made preoperatively. The cysts were excised successfully during a Whipple procedure. Awareness of this rare condition combined with modern x-ray, sonographic, and endoscopic techniques permit accurate preoperative diagnosis.

Adult↗

[Low-field magnetic resonance tomography with an iron-shielded resistive magnet].

As an alternative to costly MRI systems with superconductive magnets, first experiences with an iron-shielded resistive system (Tomikon BMT 1100, Bruker Medizintechnik--Rheinstetten) are reported. The magnetic field strength is 0.235 T, corresponding to a proton resonance frequency of 10 MHz. Our system is used mainly for research, the image quality being comparable with that of superconducting systems. Especially favourable is the low magnetic stray field of the self-shielding system. It allows unproblematic handling of patients in a clinical environment. Economic aspects are not discussed.

Brain Diseases↗

[Diagnostic and therapeutic aspects in the treatment of bee venom allergy].

In 50 patients who had severe allergic general reactions after a bee sting clinical and immunological parameters were examined under the desensitisation with apitoxin. Under the introduction of the hospital treatment 25 patients showed side effects. 14 of these patients had milder general reactions also during the further continuation of the ambulatory treatment. In no case the treatment had to be stopped. The behaviour of the specific IgE and IgG antibodies does not allow a prognostic evidence concerning possible side effects and is little suited for the individual case also as objective parameter of success. 17 patients who during the first weeks after the beginning of the therapy spontaneously had been stung by a bee did not show any reactions or only reduced reactions. This result shows that the desensitization of desensitized patients gives a secure protection from life-threatening incidents. Open remains among others the problem of the objective judgment of the therapy and thus the question of the duration of the treatment.

Adolescent↗

[Lymphographic detection of a vertebral lymphangioma].

A case of lymphangioma of the 11th and 12th thoracic vertebral body with considerable diagnostic difficulties is reported. The course of the disease could be followed roentgenographically for six years backwards. The diagnosis is confirmed by lymphangiography: lymphographic contrast medium can be demonstrated within the vertebral spongiosa. In the last months, an osteolysis of the right 11th rib was observed, being in the immediate neighbourhood of the vertebral lesion. The probable pathogenesis, the clinical presentation, and the therapeutic possibilities are discussed.

Adult↗

Budd-Chiari-Stuart-Bras syndrome: clinical, sonographic, radiological reexaminations in occlusive diseases of hepatic veins.

Ten patients with clinically and histologically verified Budd-Chiari-Stuart-Bras Syndrome (i.e. occlusive disease of small or large efferent hepatic veins) were re-examined, the examination also including combined ultrasonography and computed tomography. These non-invasive methods help to establish a quick diagnosis by locating and defining the most severe changes, by helping to select the most appropriate invasive diagnostic procedure, and by defining their topographical target. They thus facilitate immediate, optimal therapy. The disease process often starts in the right dorsal lobe of the liver and may cause extreme hyperplasia of the left or middle lobes, causing gross changes in the shape of the liver and considerably displacing the gallbladder in some cases. Thrombosis of the portal vein and pulmonary embolism seem to be most frequent complications or accompanying diseases. We therefore suggest immediate long-term anticoagulation, provided portal hypertension is not too severe; patients with severe portal hypertension should undergo a shunt operation. Our patients were followed up for periods ranging from 3 to 8 years. The very variable prognosis includes complete cure and good compensation over a long period and appears to be much better than has been reported by some authors.

Adult↗