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Biomedical subjects

W Wagner

Publications and source records attributed to W Wagner.

At least 325 records · Page 18Linked to original sources

The below-the-knee amputation for vascular disease.

Of 190 consecutive patients with below-the-knee amputation done for diabetic or arteriosclerotic vascular disease, 167 were successfully fitted with a prosthesis and used the prosthesis in some or all of the activities of daily living. The surgical failure rate was 4.2 per cent; only eight patients required surgical revision to a higher level of amputation. The technique of rigid plaster dressing followed by delayed application of a plaster cast and pylon was not detrimental to wound healing and did not increase the interval between surgery and the use of the prosthesis, nor did it depress the eventual level of function. When compared with our own previous experience with other flaps, the long posterior flap offered a significant advantage in healing rate.

Amputation, Surgical↗

A combined sensor suitable for telemetering respiratory functions.

A system for measuring oxygen consumption from momentary respiratory values of free moving person is described. The main part presented here is a sensor consisting of a flowmeter based on the impeller principle, called 'Wirbelrespirometer', joint with a polarographic electrode sensitive to oxygen, and a very fast reacting thermistor. First comparative studies in computation of respiratory volume and oxygen consumption yielded average deviations against comparison methods of less than +/- 1% for computation of volume, and +/- 4% for computation of oxygen consumption.

Electrodes↗

[Effect of nutritive measures on an antibody].

Patients of the surgical department of the university of Erlangen were investigated in regard of the influence of a complete parenteral nutrition on the reaction of tetanus anti-bodies. It was shown that by parenteral nutrition with amino-acids, carbohydrates and electrolytes with a nitrogen calory quote of 150 the immunresponse in contrary to a nutrition regime without amino-acids is markedly improved.

Amino Acids↗

Risk factors in local surgical procedures for diabetic gangrene.

One hundred and seventy-two diabetic patients undergoing local operations of the foot distal to the ankle joint were reviewed to explore the preoperative prognostic indicators of operative failure. Severity of infection, as measured by preoperative temperature and white blood count, correlated with that of failure. Subcutaneous gas, as seen roentgenographically, was associated with failure in five of six patients. No particular operation or type of wound and no general or specific medical or laboratory parameter correlated with failure. In the four and one-half years of the study, an improved operative success rate could only be correlated with improved preoperative management of infection, as reflected in a declining yearly preoperative white blood count and temperature. Delay of the operation until maximum medical control of the infection has occurred should improve the initial success rate in these patients.

Age Factors↗

[Prospective clinical studies on stress ulcer (author's transl)].

In a prospective clinical study, 100 seriously ill patients were investigated in regard to the risk of stress ulcer. It could be shown that raised shock indices with simultaneous low hemoglobin, hematocrit, albumin and serum calcium levels, as biologically measurable quantities, suggest a danger of stress ulcer.

Adult↗

[Vitamin A and stress ulcer (author's transl)].

The serum level of vitamin A can be considerably raised by parenteral administration of high doses of vitamin A. It could be showed that patients who develop stress ulcer do not have vitamin A levels below the normal. With this series of isotemporal, alternating treatments we could not confirm the favorable experience of others.

Adult↗

Nonclostridial gas gangrene. Report of 48 cases and review of the literature.

Gangrenous lesions accompanied by evidence of subcutaneous gas usually are diagnosed as "clostridial gas gangrene." The occurrence of nonclostridial gas gangrene has been infrequently reported and is thought to be relatively rare. Review of 278 admissions of diabetic patients with orthopedic vascular problems disclosed a 17% (48 patients) incidence of nonclostridial gas infections and a 3% (one patient) occurrence of clostridial gas gangrene. Clinical characteristics ranged from severe to benign toxicity. Appreciation of the causative organisms (usually mixed Gram-negative rod and enterococcus) of this syndrome is essential, especially in the diabetic patient, since appropriate antibiotic therapy and surgery can result in a low mortality (4%) and a high incidence (80%) of ambulatory, independent patients.

Acute Disease↗

[Treatment of renal hypertension by nephrectomy in persons over 40 years of age].

42 patients aged over 40 years at the time of nephrectomy (between 1961 and 1972) for unilateral renal disease and arterial hypertension were re-investigated. The WHO criteria for normotensive and hypertensive blood pressure levels were used. Systolic and diastolic pressures returned to normal after nephrectomy in 15 patients, systolic pressure alone in nine. Systolic and diastolic pressures remained unchanged in twelve. When grouped by histological criteria, only patients with small pyelonephritis kidney improved significantly, while those with pyelonephritis, arteriolosclerosis and renal-artery stenosis did not. It is concluded that patients aged over 40 years who have hypertension associated with unilateral renal disease may benefit from nephrectomy, especially if they have a small pyelonephritic kidney.

Adult↗

[The effect of acetyl-salicylic-acid and a pyrido-pyrimidine-derivate on the rejection of allotransplanted canine kidneys (author's transl)].

The effects of anti-thrombotic drugs-Acetyl-salicylic-acid and 2-Piperazinly-4-thiomorpholino-pyrido(3,2-d)-pyrimidin-sulfat-trihydrat-on rejection reactions of renal allografts in dogs have been studied. From the clinical point of view no effectiveness of the two drugs can be found, whereas the histological findings do clearly show diminished rejection reactions in the Acetylsalicylic-acid group.

Animals↗

[Indications for cutaneous ureterostomy. Experience with 117 cases (author's transl)].

74 cases of cutaneous ureterostomy and 22 cases of in situ fistula of the ureter are reviewed. Cutaneous ureterostomy was mostly carried out as a palliative procedure in cases of far advanced bladder or gynecological cancers. 13 patients had complications that required surgical intervention (7 ureteral stricture, 6 cases of pyonephroses caused by stone formation). The in situ fistula mostly served as temporary urinary diversion before definitive reconstructive surgery of the urinary tract was feasible. All patients had chronic urinary tract infection. We consider ureterostomy in situ and cutaneous ureterostomy as safe, rewarding procedures for this type of patients.

Aged↗