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Biomedical subjects

W T Cooke

Publications and source records attributed to W T Cooke.

At least 145 records · Page 8Linked to original sources
PubMed1969

Immune response to gluten in adult coeliac disease.

Cultures of mesenteric node lymphocytes obtained from two adult coeliac disease patients were stimulated by gluten fraction III. No stimulation was observed in cultures of axillary node lymphocytes from one of these patients, of mesenteric node lymphocytes from the two patients with other diseases or of peripheral blood lymphocytes from adult coeliacs and normal subjects. Peripheral blood lymphocytes of two of the six adult coeliac patients responded poorly to phytohaemagglutin alone, but this was probably owing to technical factors. In a further six adult coeliacs skin tests to gluten fraction III were negative. It is suggested that delayed hypersensitivity to gluten is likely to have a secondary pathogenic role in adult coeliac disease.

Adult↗
PubMed1969

Serum alkaline phosphatase in adult coeliac disease.

The total alkaline phosphatase levels were determined in 118 patients with adult coeliac disease, 65 of whom had evidence of osteomalacia.The secretor and blood group status, intestinal isoenzyme, and liver alkaline phosphatase played no significant part in the levels of serum alkaline phosphatase found. There was a significant correlation between the levels of serum alkaline phosphatase and the presence of osteomalacia.

ABO Blood-Group System↗