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Biomedical subjects

W Strecker

Publications and source records attributed to W Strecker.

78 records · Page 5Linked to original sources
PubMedDate not supplied

Suitability of external fixators for use in the tropics.

External fixation systems proved to decrease the osteomyelitis rate in patients in the tropics compared with internal stabilization. This study was designed to show how external fixators being used for treatment of patients in industrial countries compare with cheap alternatives regarding their suitability for the application in tropical countries. Eleven external fixation systems were compared for stability, cost, weight, variability, handling, and capability of being produced locally. Stiffness, slipping moment, and irreversible deformation were determined in material testing machines. The technically best fixators are expensive and cannot be manufactured locally. The inexpensive constructs lack variability and stability. When cost is not a problem, the Synthes model is recommended. With some restrictions in mechanical stability and variability, the Pfeifer Fixator II and a wooden model offer inexpensive and locally producible alternatives. These results may help to select an external fixation device to meet local needs and possibilities in tropical countries.

Biomechanical Phenomena↗
PubMedDate not supplied

[Echographic diagnosis of hepatic abscess (General Referral Hospital, Gbadolite, northern Zaire)].

The two most important liquefying liver diseases are the pyogenic and the amoebic liver abscess. The clinical, pathomorphological and ultrasonographic evolution is of some regularity. So a classification in three stages is of practical usefulness. The ultrasonographic characteristics of those stages for the two forms of liver abscess are presented as well as their specific treatment.

Democratic Republic of the Congo↗
PubMedDate not supplied

[Insulin and glucagon in the blood plasma of partial hepatectomized rats (author's transl)].

Up to 4 weeks after partial hepatectomy the concentrations of immunoreactive insulin and glucagon in the blood plasma of rats were determined. Furthermore we measured the activity of acid phosphatase in the serum, the concentration of cyclic AMP in liver cells, the activities of acid phosphatase in whole liver cells and in the cytosol of liver cells after partial hepatectomy. 2 h after partial hepatectomy there was a decline of the concentration of insulin in the plasma to about 13% of the initial value. 12 h after surgery a 5-fold increase of glucagon was found in the plasma. Shortly after this cyclic AMP reached its highest concentration. The activity of acid phosphatase in the whole liver cells and in the cytosol decreases slightly in the first 24 h after surgery whereas there is an increase of the activity of acid phosphatase in the serum.

Acid Phosphatase↗
PubMedDate not supplied

Glucagon-like immunoreactivity (GLI) in blood plasma of partially hepatectomized rats.

The concentration of substances with glucagon-like immunoreactivity (GLI) was determined in arterial blood plasma of rats up to 4 weeks after partial hepatectomy. 10 h following surgery a more than 18-fold increase in GLI + glucagon immunoreactivity could be observed. About 2/3 of the maximum activity seems to be of non pancreatic origin. The levels returned to normal about 22 h after surgery.

Animals↗
PubMedDate not supplied

Effect of pregnenolone-16alpha-carbonitrile (PCN) on rat liver.

One time i.p. injections of 5 -20 mg Pregnenolone-16alpha-carbonitrile (PCN) effects the mitotic activity of rat liver cells during a time period of 24 hours to be 20 times higher than the normal mitotic rate. This, however, does not result in an measurable increase of cell numbers and cell volumes. Furthermore, total liver DNA, RNA, protein and dry-weight remain unchanged. The injection of 7 times 10 mg PCN also results in the elevation of the mitotic rate. Return of the elevated mitotic rate to base level takes 18 days from the time the last injection of PCN was administered. During this time the number and the average volume of liver cells increases by 28% and 30%, respectively. The dry weight of liver and tetraploid nuclei increase in number, whereas RNA- and protein content remains unchanged. All parameters have reached the base line after 4 - 6 weeks following the last injection of PCN. No histological changes were observed after multiple doses of PCN that cause hyperplasia and hypertrophy of liver tissue. Hypertrophy of liver cells follows the observed hyperplasia and therefore is not expected to be the cause of the hyperplastic processes.

Animals↗