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Biomedical subjects

W Stock

Publications and source records attributed to W Stock.

At least 127 records · Page 7Linked to original sources

[Follow-up in stomach carcinoma].

For ten years after resection of stomach cancer patients were routinely examined to detect early asymptomatic recurrence, 96 records were analyzed, 21 patients with recurrence of cancer were found--3 local recurrence and 18 distant metastases. There was no anastomosis recurrence, 20 of these patients had clinical symptoms. About 90 percent of all recurrences were found in the first two years. After diagnosis of recurrence the one-year-survival-rate was only eight percent. We believe that the regular follow-up following resection of stomach cancer is not an effective method of detections asymptomatic curable recurrence. For this reason we recommend intensifying individual care and decreasing endoscopic or radiological examinations.

Adenocarcinoma↗

[Post-traumatic soft tissue defects of the foot].

The weight-bearing areas of the foot have a special tissue structure. When reconstructive surgery is performed care must be taken to prevent unstable scars and ulceration. The authors present methods of soft tissue reconstruction.

Foot↗

[Plastic surgery measures in combined soft tissue defects of the lower leg].

Isolated or combined soft tissue defects of the lower leg are still a challenge as regard diagnostic and differential treatment. We distinguish acute and chronic isolated or combined soft tissue defect. Acute trauma within a multiple injury pattern is a special form of the acute soft tissue defect. For diagnostic purposes we use a preoperative and intraoperative standardized diagnostic programme. A new classification oriented towards the therapeutic procedure is presented, as is therapy algorithm which has been created.

Follow-Up Studies↗

[Vascularized periosteal transplant. A review of a new therapeutic possibility].

The idea of using vascularized periosteal flaps in reconstructing bone defects is more than one hundred years old. Up to now, experimental and clinical results regarding their osteogenic capacity have been a subject of debate. Experimental and clinical studies over the last ten years were able to demonstrate osteogenic capability of such vascularized periosteal flaps, provided the periosteum is well vascularized. To insure intact microcirculation, vascularized periosteal flaps must be freed up by sharp dissection. Small pieces of bone may be removed with the periosteum, whereas the periosteum must remain uninjured. There are many known donor sites in man: the iliac crest, the distal femur, the distal humerus and the tenth rib. There are no reports concerning donor site morbidity. Besides its osteogenic capacity, the periosteal flaps have "shape giving" and "space limiting" functions. The given volume within a periosteal flap rolled into a tube is the basis for the "Concept of the Given Space": the space within the tube defines where bone formation will occur, there being no loss of bone into the surrounding soft tissue. Because of the vascularized periosteal flap's fragility and the good results of other reconstructive procedures for segmental bone defects, there are few indications for extremity reconstruction using periosteal flaps: pseudarthrosis in the upper extremity is one example. In the lower extremity, a combination of vascularized periosteum with conventional and mainly vascularized bone grafts offers interesting possibilities for reconstruction.

Animals↗

[The effect of age and sex on localization, tumor stage and prognosis of colorectal carcinoma].

In a retrospective study including 946 cases with colorectal cancer we analysed age, sex, distribution and stage. There was a significant higher prevalence in women and in all tumor stages women were older than men. The frequencies of Dukes C and proximal colon cancer was significantly higher in women. In older patients we found an increasing incidence of proximal cancer. Instead of tumor stage the age, sex and distribution showed no influence on the outcome.

Aged↗

Ultrasonic endoluminal examination in the follow-up of colorectal cancer. Initial experience and results.

We have been using endoluminal ultrasonography since 1988 as part of the follow-up procedure after colorectal surgery. A total of 106 patients with anterior resection of the rectum or the sigmoid colon were involved in 1988. The follow-up period for these patients ranged from 1 to 56 months after surgery (23.1 +/- 15.1 months after anterior resection of the rectum; 25.7 +/- 22 months after anterior resection of the sigmoid). During the observation period 7 patients developed recurrence after anterior resection of the rectum and 5 after anterior resection of the sigmoid. The primary stages for these patients had been 7 cases of Dukes' B, 3 of Dukes' C1 and 2 of Dukes' D. Raised serum CEA levels were found in 5 cases. In 3 other cases, we found pathological changes in the anastomotic region by means of endoscopy. In these the endorectal ultrasonic scan showed hypodense masses as a sign of recurrence. In 2 of these 3 cases, the serum CEA level was normal. In 4 cases endoluminal rectal ultrasonography alone was suspicious. This led to further diagnostic procedures and finally to radical excision. All suspicious ultrasonic images were monitored 2 to 4 weeks later. In cases of suspicion, endoscopic, needle or surgical transrectal biopsies were taken from all patients. In all cases, histological analysis confirmed the ultrasonic diagnosis of local recurrence.

Aged↗

[Clinical basic documentation in surgery].

Clinical basic documentation allows a cost lowering and personal saving application of modern data processing technology within the clinical routine. The concept presented in this article has been successful for ten years. Soon after its installation this documentation provides its user with valuable data for internal quality control. Listings of diagnosis, surgical procedures, length of stay and frequencies of complications can be created without extensive knowledge of data processing and computer programming. Based on this concept special documentations for statistical analysis of certain patient groups or diseases are easily established.

Documentation↗

[Air transportation of patients: a danger of hypoxic organ lesions?].

As illustrated by two cases, a fall in alveolar oxygen pressure at high altitude, such as during transportation by plane, can cause hypoxic pulmonary failure, especially in patients with already impaired pulmonary or circulatory functions. Arterial oxygen saturation was recorded by pulse oximetry in 14 healthy volunteers and eight patients during air transportation. Oxygen saturation decreased with reduced cabin pressure. Decreased saturation for each 100 mm Hg reduction in cabin pressure was markedly greater in the patients than the healthy volunteers. Pulmonary and circulatory status should be assessed before air transport of patients and if necessary departure delayed. Oxygen ought to be added to inspired air with appropriate supervision in all acutely ill patients. Indications for endotracheal intubation before flight should be generously defined. Continuous pulse oximetry is noninvasive and highly informative. It is urgently recommended that air ambulances be equipped with them.

Adult↗

[Routine gastroscopy before cholecystectomy].

We are of the opinion that the investigation of the upper gastrointestinal tract must precede an elective cholecystectomy. In a prospective study the value of preoperative oesophagogastroduodenoscopy preceding elective cholecystectomy is considered. 589 gastroscopies were performed in our endoscopy unit on 960 patients coming to elective gallbladder surgery. Only in 56% of patients we detected no abnormalities. Our plan of therapy was changed in 113 patients (11.7%). 11 patients were discharged after conservative medical therapy (1.1%), in 31 cases simultaneous procedures were performed (3.2%). After additional medical treatment 71 patients came to elective cholecystectomy (7.4%).

Cholecystectomy↗

[Follow-up care in colorectal adenoma].

From 1980 to 1985, 319 adenomatous colorectal polyps were removed in 297 patients. All patients were entered into a computerized follow-up programme with yearly follow-up. The recommended follow-up was rejected by 58 patients (22.1%). 93 new adenomatous polyps were found in the course of the follow-up in 53 patients (35.8%), five of them histologically invasive carcinomas. The proportion of carcinomas was lowered from 10.6% at first examination to 5.4% in the follow-up period. Size of polyp correlated significantly with carcinomatous change. Size of the adenomas removed at follow-up was markedly smaller than that removed at first examination (69.4% smaller than 1 cm compared with 44.2% at follow-up). In six patients with early invasive carcinoma, further resections were undertaken, while in six others only the polyps were removed. But local recurrences occurred in both groups. Regular follow-up after polypectomy of colorectal adenoma is thus essential.

Adolescent↗

[Effect of lipid emulsions on nitrogen balance within the scope of perioperative parenteral feeding regimens].

Patients with colorectal cancer were parenterally fed before and after surgery by two different isocaloric regimens: One group was infused with high carbohydrate solutions (carbohydrate group), the other group with carbohydrate in combination with fat emulsions (fat group). The daily dose of fat was restricted to 1 g fat/kg BW/day. These conditions led to the following results: No significant changes in the protein balance were observed between the patients of the two regimens. The protein sparing effect and the synthesis of short living proteins were comparable. The infused fat emulsions were utilized without metabolic complications. Patients in the fat group were adequately supplied with essential fatty acids which was documented by the higher level of linolic acid in the blood. The biochemical and histological analysis of the liver samples which were excised on occasion of surgery gave comparable triglyceride content in both groups. In the fat group little lipid deposition was seen in the parenchymal cells but lipid droplets were observed in the reticuloendothelial system (v. Kupffer cells). Thus, distribution of fat droplets is different in the 2 groups. Unfortunately analysis of lipid depositions in the liver at the end of the parenteral nutrition could not be performed.

Adenocarcinoma↗

[Value of intra-arterial digital subtraction angiography in microvascular anastomosis in tissue transplantation].

The technique of selective intraarterial digital subtraction angiography is less time-consuming and requires less contrast medium than conventional angiography thus reducing both the invasiveness and the risk associated with angiography. With this method both the morphology and the functional status of the vasculature can be determined. Anatomic variations in the blood supply which influence the operative technique can thus be known preoperatively and no longer threaten the success of the operation.

Angiography↗

[Anatomy and clinical aspects of sartoriusplasty].

According to Mathes and Nahai (1982) the sartorius muscle is supplied in a segmental fashion (Type IV) from six to ten branches arising from the superficial femoral artery. They state that the use of this flap is limited because of the segmental blood supply. In contrast, dissecting 40 cadaver specimens at the Anatomy Department of Munich University a different vascular anatomy was revealed in which only two to four branches from the femoral artery supply the whole muscle. Based on this pattern of intramuscular vascular connections, the most proximal arterial branch provides the blood supply to the whole muscle. Elevated on the proximal vascular pedicle the muscle can cover defects of symphysis, fill the acetabulum following disarticulation of the septic hip joint and osteomyelitic defects of femur.

Arteries↗