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Biomedical subjects

W Smith

Publications and source records attributed to W Smith.

At least 343 records · Page 19Linked to original sources
PubMed1978

Neutrality or negligence: interpret or act?

The uniqueness of the psychotherapeutic relationship requires the therapists to maintain a careful equilibrium between objectivity at the price of empathy and closeness at the expense of the necessary perspective. Crises in the course of long-term psychotherapy brings about a sudden, unexpected loss of such equilibrium. Uithout sufficient understanding of the crisis within the context of the therapeutic strategy and goals, the therapist might easily over- or underreact, to the detriment of the treatment. In this paper we suggest careful scrutiny and guidelines for dealing with those situations.

Adult↗
PubMed1976

Fat embolism associated with an atrial septal defect.

A case of a patient with pulmonary fat embolism following fractures of femurs and pelvis, with a fatal outcome after 3 days, is presented. Post mortem examination revealed a congenital osteum secundum heart defect, and widespread capillary occlusions from systemic fat microembolization.

Aged↗
PubMed1976

A rotavirus in lambs with diarrhoea.

A reovirus-like agent was identified from an outbreak of enteritis in young lambs. From its morphology and immunological relationship with calf rotavirus, it was concluded that it was a rotavirus which infects lambs.

Animals↗
PubMed1975

Appearance of C-type virus-like particles after co-cultivation of a human tumor-cell line with rat (XC) cells.

A serially progagated cell line (L104) was established by co-cultivation of alung adenocarcinoma (L-1) from a patient with concurrent chronic lymphocytic leukemia and XC, a non-producer rat line, known to carry the Rous sarcoma virus (RSV) genome. Karyotype of the L104 cultures revealed predominantly rat-like patterns; however, about 5% of the cells reacted with HLA antibodies and demonstrated human isozyme patterns. Electron microscopy of L104 cells revealed the presence of C-type particles budding from the cell membranes and in cytoplasmic vacuoles. Virus was not detected in any of the other normal lung, lung tumor or XC cells examined after co-cultivation with XC cells. The particles isolated from tissue culture fluids had the biochemical and biophysical characteristics common to other known mammalian C-type particles and were serologically related to the woolly monkey virus (WMV)/gibbon ape leukemia virus (GaLV) complex. Cross-hybridization between viral 3H-DNA transcripts and cellular RNAs from virus-infected cells clearly show the presence of sequences in the L104 cellular RNA related to both the GaLV/WMV group of viruses and rat viruses. Hydroxyapatite chromatography reveals however that the primate-related sequences in the viral RNA are indistinguishable from WMV in thermal elution profile. The host range of L104 virus appears to vary greatly from WMV in being xenotropic and, in the cell lines thus far tested appears, to infect only rat cells. The virus gave positive KC but negative XC assays. Inoculation of whole cells or cell-free supernatants into weaning hamster did not result in either solid tumors or leukemia. Co-cultivation of appropriate cell lines may represent an approach to the detection of latent viruses in human neoplasia.

Adenocarcinoma↗
PubMed1975

Hepatic artery traumatic aneurysm.

The diagnosis of intrahepatic aneurysm was suspected following radioisotope scintigraphic studies. A patient developed abdominal pain following blunt abdominal trauma. The scintigrams of the liver revealed a large intrahepatic defect and separation between lung and liver. Angiogram revealed a large false aneurysm of the right hepatic artery.

Adult↗