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Biomedical subjects

W Schulz

Publications and source records attributed to W Schulz.

At least 145 records · Page 8Linked to original sources

[Reciprocal relationship between bones, hematopoiesis and kidney with reference to sex hormoses. 2. Endocrine osteopathy and sex hormones].

Interactions and influence between blood and bone-tissue are discussed. In chronic renal insufficiency there is a failure of the kidneys as an endocrine organ with hormones for hemopoiesis and bone-metabolism. This deficit can partly or completely be replaced by an appropriate therapy. The--in the kidney transformed and so activated--vitamine-D-metabolite 1,25(OH)2D3 can be used in the therapy of osteoporosis, the combination with sodium fluoride brings even better results. In cases of postmenopausal osteoporosis and lack of estrogen estrogens are indicated for the treatment and the prophylaxis of osteoporosis.

Adult↗

[Home dialysis].

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Acute Kidney Injury↗

[Kinetics of supporting teeth in patients with partial dentures].

In 2 female patients with partial prostheses in the lower jaw, a pilot study was undertaken by means of inductive distance measures into the kinetics of supporting teeth during blank mastication over a period of 10 weeks. 1. Already at the beginning the end supports show unphysiological characteristics of movement during pressing and rubbing. 2. The existing canine guidance shows no abnormal kinetics of the supporting teeth during the excursions. 3. The direction of the kinetics of the supporting teeth changes in embedded part prostheses. 4. The abutment teeth show higher kinetic values after 10 weeks (without embedded partial prosthesis) than in the beginning. 5. In embedded partial prostheses all kinetic values closely approach the physiological norm. The directions on the other hand do not correspond with the physiological norm. The partial prosthesis acts as a splint for the abutment teeth.

Adult↗

[New method of estimating x-ray magnification on angiographic volume determinations (author's transl)].

1. The necessity of a precise determination of the magnification factor for angiographic volume determinations is described. Each error of the linear magnification factor influences in its third power the volume calculation. 2. For the magnification of linear cineangiographic magnification a method is used in which the tip of the catheter is filmed in two positions. The distance approximately resembles a normal ventricular diameter. The relationship of virtuel shifting of the catheter tip versus real shifting of the patient is the magnification factor. 3. For the practicable handling of this method a new developed mechanical device is described which allows the performance of the calibration procedure with an adequate high precision. 4. The method is simple and can be done within a short period of time.

Angiography↗

[Home dialysis (author's transl)].

100 patients requiring dialysis were trained between 1970 and 1975. Up to 31. 12. 1975, 56 patients were on home dialysis, 10 on the self-care program and 6 were freshly trained. Training usually lasts 8 weeks. The training course is briefly presented and the supervision of home dialysis patients after discharge from training is described. The possibility of vacation plays an important role in social rehabilitation. Since the spring of 1976, the hospital has operated a camping dialysis bus, the use of which is reported.

Adolescent↗

[Kidney transplantation from a nephrological-urological viewpoint--results and problems. 2. Diagnosis and therapy after transplantation, complications, long-term results].

Indications, selection of donor and recipient, medical and surgical management and complications, problems of organ procurement. Renal transplantation has become routine therapy. Organs are predominantly obtained from cadavers, transplantations from living donors are rarely indicated. Advances in preservation methods have improved organ quality and prolonged storage time. Selection of the most suitable recipient is based on histocompatibility matching. Blood transfusions before transplantation seem to improve the results. Recognition of a rejection crisis is primarily based on clinical symptoms. Persistent rejection calls for prompt explantation and the patient has to return to dialysis. Infections, serum-hepatitis and gastro-intestinal bleeding are the most common complications. Late complicatons are diabetes mellitus, cirrhosis of the liver, osteopathy, recurring glomerulonephritis, and, rarely, malignomas. Transplantation frequency in the Federal Republic of Germany could be increased by more awareness of physicians and a better knowledge of the general public about the need for cadaver donors.

Graft Rejection↗

[Home dialysis].

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Adolescent↗

[Care of the hemodialysis patients by the family physician].

Cooperation between the family physician and the kidney-center begins with the recognition of a renal disease and pre-dialysis treatment. Our patients usually are sent for the preparation of an arterio-venous shunt operation (Cimino or modifications) when serum creatinin levels amount to 8 to 10 mg/100 ml. Peripheral veins on both forearms should be reserved for these procedures early in the course of renal disease and vascular punctures should be avoided. Dialysis treatment is performed either at the kidney-center, at one of our partner-centers, at the central self-care facility operating under the care and supervision of the kidney-center or as home-dialysis-treatment. Each patients continues to receive technical and medical services of the center. Central self-care dialysis as well as home-dialysis are organized by the Kuratorium for Heimdialyse e.V. in this area. This organization also provides an on-cell-service of technicians. Nurses and physicians take regular rotations to staff the dialysis- and the self-care-units. The family physician takes care of the hemodialysis patinet in cooperation with the hospital. In case of medical problems the patient is transferred to the kidney-center. The patient must be well instructued on problems and complications which might occur during hemodialysis, either due to the basic disease or in connexion with hemodialysis. In some cases of complications patients must be admitted to the center without delay. Emergency situations usually can be avoided as technical standard of dialysis equipment and standard of training of patients or their parners is high. Medications, such as phosphate binders (aluminium hydroxide), iron vitamins and allopurinol are provided if necessary. Patients are advised to limit intake of fluids and potassium containing foods. The sodium intake depends on blood pressure-values. In case of hypertension there will be salt restriction, in case of hypotension the salt intake is increased. Chronic intermittent hemodialysis treatment can result in successful rehabilitation. Further improvement concerning personal and medical problems can only be expected from kidney transplantation.

Family Practice↗

[Studies on calf salmonellosis. 3. Preclinical evaluation of a Smd. Salmonella dublin live vaccine].

Results of preclinical assay, preparation and conservation of a S.-dublin live vaccine based on streptomycin dependent mutants and for oral application are demonstrated and discussed in detail. The used oral vaccine is very good tolerated by calves and results in stable immunity after administration of a daily dose of 5 x 10(10) bis 1 x 10(11) living Smd.-mutants for 10 consecutive days. Complete immunity developes in calves within a period of two weeks after the last antigen administration and persists up to the age of 5 to 6 months. Conserving the vaccine at low temperatures (-15 degrees C) the number of living organism is far-reaching preserved in the first 5 months after preparation. After thawing the vaccine is to be used within a period of 3 days. With respect to the preparation of the live vaccine on semisynthetic nutritiv media some informations are given concerning the improvement of bacterial yield.

Administration, Oral↗

[Studies on Salmonellosis in the calf. 5. Clinical testing of Smd-Salmonella-dublin vaccine for oral administration].

The oral vaccine, prepared on the basis of streptomycindependent mutants for administration to control S.-dublin infection, was clinically tested on 2,210 calves of 22 herds. The experimentally obtained findings regarding good tolerance and sufficient effectiveness of oral live vaccines were thus confirmed under field conditions. Good effectiveness of the oral vaccine was reflected in the recorded decline of clinical salmonellosis cases and of calf losses due to salmonellosis, and it was established also by bacteriological identification of S. dublin in faecal samples, histological sections, and material obtained from emergency slaughter carcasses. A comparison between this oral vaccine and "Mellavax" an imported vaccine for subcutaneous adminstration with good effectiveness, revealed superiority of the oral vaccine by almost all criteria of action. Particular importance was attributed to the significant reduction of the number of Salmonella-excreting animals (faeces) following oral immunisation. The oral vaccine against Dublin salmonellosis of calf was disembargoed for production in 1975 under the name of "Salmonella-dublin Live Vaccine Dessau".

Administration, Oral↗