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Biomedical subjects

W Schmitz

Publications and source records attributed to W Schmitz.

At least 235 records · Page 13Linked to original sources
PubMed1978

[Haemochron--a simple method of monitoring heparin level during extracorporeal circulation].

Tow forms of heparin management during cardiopulmonary bypass were compared in order to analyze the role of the heparin level in relation to postoperative blood loss. The study was divided in three groups: In group I, the control group, 3 mg/kg body weight heparin was given as an initial dose and maintained at a dose of 1.0 mg/kg every 60 min during cardiopulmonary bypass; group II received the same initial dose, but additional doses were based upon the activated clotting time measured with a Haemochron; in group III, the Haemochron time was measured at 10-min intervals to establish a base value. In group II we found a significant decrease in postoperative blood loss as well as a decrease in the amount of heparin administered during cardiopulmonary bypass. In addition, fewer transfusions were required in the immediately postoperative period. In group III, wide variations in the activated clotting time curve were observed. No patients was underheparinized, but some had markedly prolonged Haemochron times.

Blood Coagulation Tests↗
PubMed1977

[Heart tumors].

Explore the source record for details and available documents.

Heart Neoplasms↗
PubMed1976

[Iatrogenic foreign bodies in heart (author's transl)].

Two cases are reported of migrating Kirschner wires, which had been inserted for stabilisation of bony defects of the thoracic cage. The wires migrated in both patients to the heart and caused life threatening complications like pericardial tamponade, arrhythmias and cardiac insufficiency. Indications for removal of foreign bodies from the heart are discussed. Attention is drawn to the fact that the ends of Kirschner wires must be bent in order to prevent migration.

Adolescent↗
PubMed1976

[Survival of 51cr-tagged red blood cells in patients with artificial heart valves (author's transl)].

Survival of 51Cr-tagged erythrocytes is determined in 10 patients approximately 1 week after insertion of an artificial heart valve ("early hemolysis") and in 9 patients approximately 2 years after heart valve replacement ("late hemolysis"). Red blood cell survival is found to be significantly reduced in all patients following insertion of an artificial heart valve as compared to a group of control patients. Hemolysis is significantly more pronounced in the early postoperative phase than two years postoperatively. LDH and plasma hemoglobin are relatively good indicators of hemolysis but less reliable than the determination of t/2 Cr.

Adult↗
PubMed1975

[Postoperatives acute renal failure after operations with extracorporeal circulation (author's transl)].

An acute renal failure was observed postoperatively in 3,45% of 929 patients operated with the heart lung machine during the years 1970-1972. Because of the bad results of any therapy in the case of acute postoperative renal failure, the diagnostic procedures of the preoperative renal function were intensified of the preoperative renal function were intensified in order to prevent an acute postoperative renal failure. Therefore additional measurements of the creatinine clearance and in few cases radioisotopic clearance tests were done.

Acute Kidney Injury↗
PubMed1975

[Results of electrical pacing in patients with hypertrophic obstruction cardiomyopathy (author's transl)].

In patients with hypertrophic obstructive cardiomyopathy, left ventricular outflow gradient decreased about 56 per cent by way of electrical stimulation of the apex of the right ventricle. In 4 patients a permanent pacemaker was implanted. P-wave triggered pacemakers with electronic conduction-time of approximately 0 sec showed to be preferable. The decrease of left ventricle outflow gradient as well as of subjective complaints inclusively cerebral syncopes were remarkable.

Adult↗
PubMed1975

[Isolated rupture of the interventricular septum after blunt chest trauma (author's transl)].

The mechanism, symptoms and treatment of traumatic ventricular septal defect are discussed on the basis of an own observation. To the best of our knowledge this is the first report of a rupture of the membranous septum, involving the portion between the left ventricle and the right atrium. An attempt is made to explain the mechanism of isolated traumatic ventricular septal rupture on the basis of embryological considerations. The patient died on the 11th postoperative circulatory status and inspite rather prompt diagnosis and operative treatment.

Accidents, Occupational↗
PubMed1975

[Tryptophan metabolism research in oligophrenic children. 4.: Activity and possibility of activating hepatic kynureninase after vitamin B6 treatment].

In 8 selected test persons of the 3rd series of experiments who were showing signs of pathological kynureninase activity, hepatic kynureninase was again established after 3 week's treatment with large doses of vitamin B6. The enormous in-vivo activation of the kynureninasis established goes to prove that apoenzyme synthesis may be stimulated by pyridoxine. On the basis of these results and the relative frequency of disorders dependent on B6, the question arises whether children from endangered families should not be given prophylactic vitamin B6 treatment from birth.

Adolescent↗
PubMed1975

[Determination of kynureninase activity in oligophrenic children with hereditary taint, before and after vitamin B6 treatment].

Kynureninase activity assay in oligophrenic children with hereditary taint, before and after treatment with vitamin B6. The hepatic kynureninase activity was assayed in 25 oligophrenic children with hereditary taint, and having a positive tryptophan load test. Eight cases (32%) showed an enzyme activity below the 2-s limit; in two cases, the pathologic enzyme activity could be almost normalized by addition of higher P-5-P concentrations. In a second set of studies, eight children with an abnormally low kynureninase activity were re-examined following a 3-week treatment with vitamin B6. The enormous in-vivo-activation of kynureninase reached in these studies lends support to the assumption of a vitamin-B6-dependent "inborn error of metabolism" in the tryptophan-kynurenin pathway in some of the investigated oligophrenic children with hereditary taint.

Adolescent↗