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Biomedical subjects

W Richter

Publications and source records attributed to W Richter.

At least 235 records · Page 13Linked to original sources

[Not Available].

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Education, Medical↗

[Incidence of caries and periodontal condition in patients with cleft lip and cleft palate].

The data relative to caries experience, provided dental care, periodontal condition, oral hygiene and pocket depth obtained from 158 patients with cheilognathopalatoschisis were recorded. According to age, the findings were subdivided into three groups: deciduous dentition, mixed dentition and permanent dentition group. The data obtained from the upper jaw were compared to those from the lower jaw. Furthermore, the data relative to the different types of tooth and the region of the cleft were compared to the findings from teeth non-neighbouring the cleft. The results permit to draw conclusions as to noteworthy aspects of the orthodontic and the general dental care of patients with cheilognathopalatoschisis.

Adolescent↗

[Autoradiography of the neurogenesis and morphogenesis of the regio cingularis in the rat. II. Proliferation kinetics in the area praecentralis agranularis].

The proliferation of the matrix-cells in the Area praecentralis agranularis of 219 embryonic rats has been investigated by means of autoradiographs, after injection of tritiated thymidine at different stages of foetal life. The course of the labeling index indicates that matrix-cells represent a cell population in which cell multiplication is both rapid and continuous. Moreover the number of labeled cells decreases following the migration of labeled neuroblasts to another site. Because the beginning of migration retards after a division a proliferative compartment and a differentiating compartment were found in the subventricular and ventricular zone. The migration appears in waves not before 24 hours after division of cells. We have found that, between the second and the third day and betw-en the third and the fourth day after injection, migrating cells arise with 1/2 or 1/4 of the number of silver grains respectively. A comparison with the values of the Regio cingularis mesoneocorticalis (RICHTER and KRANZ 1978) indicates that no differences exist between the both regions. Cell division and migration both indicate in the brain a sequential nature; after each mitosis only one of the daughtercells retains their proliferative capacity, the other becomes differentiated into neuroblast and leaves the proliferative compartment.

Age Factors↗

[Autoradiography of neurogenesis and morphogenesis in the regio cingularis of the rat. III. Migration and lamination in the regions of the cingulate cortex and the area postcentralis].

The migration has been investigated in 171 embryonic and neonatal rats by means of autoradiographs, after injection of tritiated thymidine from E 18 to P 12 in 4 regions of the brain (Mesoarchicortex, Regio cingularis mesoneocorticalis, Area praecentralis angranularis, Area postcentralis). The migration begins at the third day after the injection. The localization of labeled cells was found in the cortical plate after injection in the early embryonic period and in the L II after injection in the late phasis always at the third day, the speed of migration increases in the course of embryonic development. The migration indicates in all regions an inside-out sequence. Cells from the last division migrates to the surface of the cortical plate. The cortical plate is a transitory element of the brain development. The lamination is possible earlier by means of the distribution pattern of labeled cells than with cytoarchitectonics and also the observation of areas.

Age Factors↗

[Autoradiography of neurogenesis and morphogenesis of the regio cingularis of the rat. IV. Quantitative studies on the times of cell origins in the cortical lamina].

In 171 embryonic and neonatal rats has been investigated the time of origin of cells in the cortical laminae by means of autoradiographs, after injection of tritiated thymidine. It was made a comparison between the Regio cingularis mesoneocorticalis, Regio cingularis mesoarchicorticalis, Area praecentralis agranularis and Area postcentralis by the laminar differential labeling index. The time of origin indicates for each layer a principal day and three secondary days. In all regions the time of origin of cells is identically for the hylogenetic old layers VI and V, differences exist in the supragranular layers: the cells are generated earlier in the phylogenetic old areas than in the young areas.

Age Factors↗

[Sclerodermiform paraneoplastic syndrome during a kidney carcinoma].

Sclerodermiformous alterations of the skin are described as paraneoplasia in different malignant tumours. By an own observation sclerodermiformous alterations of the skin are described for the first time as paraneoplasmia in a female patient aged 60 with nephrous carcinoma. The cutaneous efflorescences receded after elimination of the tumour.

Female↗

Digitonin induced alterations of the erythrocyte membrane as visible by freeze-fracturing.

Treatment of erythrocytes by low concentrations of digitonin results in the formation of elongated, bulged membrane areas free from particles and intramembraneous tubular structures emerged from these domains. At higher concentrations the tubular structures are present also outside of the membrane. A second, not bulged type of particle-free areas is more or less rounded, but mostly of rectangular shape. The rate of this type of domains increases with the concentration of digitonin. Breaks in these areas lead to a formation of sheets which results in a breakdown of the membrane structure finally into a brittle mass of many small sheets lying irregularly one upon the other. Already during the first steps of this membrane breakdown hemolysis takes place. Cross-linking of the proteins with glutaraldehyde does not entirely block up the membrane alterations. In fixed erythrocytes the formation fo elongated domains is restricted, no tubular structures are present and no dislocations of particles can be observed. Nevertheless smooth sheets localized also outside of the membrane are formed. However the investigated ghosts are not stabilized by glutaraldehyde against the effects of digitonin. Particle dislocations as well as all the other membrane alterations are present. The implications of the obtained results are: 1. The elongated domains and the tubular structures are probably not digitonin-cholesterol-complexes. 2. The formation of crystalline regions by digitonin-cholesterol-complexes destroys the membrane structure.

Digitonin↗

[Not Available].

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Education, Medical↗

[Frequency, extent and severity of malocclusions in 401 dental students (Berlin )974)].

In the framework of the complex stomatological examination of 401 dental students from the Humboldt University in Berlin, the author determined, in 1974, on study casts the extent and intensity of tooth malalignment and malocclusion, using the method as indicated by Eismann. The results obtained were analysed for differences according to sex, age and former orthodontic treatment. With regard to their importance, the orthodontic symptoms are evaluated from the aspect of need for orthodontic treatment.

Adolescent↗

[Relationships between occlusal anomalies and caries, periodontal diseases, oral hygiene and temporomandibular joint disorders in 401 dental students (Berlin 1974)].

In 1974, 401 dental students of the Humboldt University in Berlin were examined for caries incidence, periodontal condition, oral hygiene and temporamandibular joint pain. The findings were brought in relation to the extent of extant tooth malalignment and malocclusion (model analysis according to Eismann). Statistical methods were employed to test existing relationship for significance, allowing for age, sex and former orthodontic treatment. The results were evaluated in view of the need for orthodontic treatment.

Adult↗

[Autoradiographic studies of the neurogenesis and morphogenesis of the cingulate region in the rat. I. Proliferation patterns in different pre- and postnatal stages].

The proliferation of the matrix-cells in the limbic cortex of 219 embryonic rats has been investigated by means of autoradiographs, after injection of tritiated thymidine at different stages of foetal life. The course of the labeling index indicates that matrix-cells represent a cell population in which cell multiplication is both rapid and continuous. Moreover the number of labeled cells decreases following the migration of labeled neuroblasts to another site. Because the beginning of migration retards after a division a proliferative compartment and a differentiating compartment were found in the subventricular and the ventricular zone. The migration appears in waves not before 24 hours after division of cells. We have found that, between the second and the third day and between the third and the fourth day after injection, migrating cells arise with 1/2 or 1/4 of the number of silver grains respectively. Cell division and migration both indicate in the brain a sequential nature; after each mitosis only one of the daughter-cells retains their proliferative capacity, the other becomes differentiated into neuroblast and leaves the proliferative compartment.

Animals↗