Progressive ataxia in Charolais cattle.
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Biomedical subjects
Publications and source records attributed to W R Kelly.
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Thermal-ionization isotope-dilution mass spectrometry is a highly precise and accurate method for the determination of potassium concentrations in serum. Although not suited for routine use because of the time and expense required, the technique provides an extremely valuable tool for the characterization of reference materials and for evaluating other analytical methods. The technique has recently been used to determine the concentration of potassium in a human serum standard, NBS Standard Reference Material 909. Seven vials of the serum were chemically processed and then analyzed by two spectroscopists independently, using different mass spectrometers. The results confirm previous work that indicates that a precision of 0.1% relative can be routinely achieved. The systematic errors in the method have been thoroughly evaluated. When the precise results are thus corrected, they are essentially bias free and hence definitive.
Stenosis of the cervical vertebral canal in a 10 1/2-month-old Suffolk ram is described. The vertebral canal was narrowed in a dorsoventral direction at the anterior and posterior ends of the cervical vertebral C3 and C4, at the posterior end of C2 and the anterior end of C5. The body of C3 was wedge-shaped in a longitudinal plane. The vertebral abnormalities are believed to have resulted from instability, perhaps exacerbated by fighting. There was a region of necrosis of the spinal cord at junction of C1-2. The animal showed sudden onset of quadriplegia from which it gradually recovered. The rams in the group were on a high plane of nutrition and two others were probably affected.
After injury to the left foreleg, a 2 1/2-year-old Great Dane bitch developed severe oedema of the limb, which did not respond to pressure bandaging or a proteolytic agent. Skin breakdown occurred over the metacarpal region and lymph could be expressed from this lesion. The oedema spread, anaemia and dyspnoea developed and the animal died of respiratory insufficiency 55 days after the initial injury. Autopsy showed widespread infiltration of subcutis, fascial planes and some muscles of the leg by invasive cords and sheets of small endothelial-type cells which formed channels sometimes filled with blood. There was widespread diffuse metastatic neoplasm throughout the lung but no cavernous blood sinus formation. There were small metastases in local lymph nodes, kidney, bone marrow and spleen. It was concluded that the injury made obvious an oedema caused by pre-existing angiosarcoma.
"Despite the long standing interest in illegitimacy as well as the importance of its consequences, and the concern which the post war upturn has generated, researchers know surprisingly little about the social, economic, demographic, and cultural factors that influence temporal variation in illegitimacy. By using annual time series data for Sweden and Australia, [the authors] examine trends in and levels of illegitimacy over a sixty year period and assess the impact of various social, economic, demographic, and cultural factors on change in illegitimacy rates. [The] primary focus is the extent to which cultural differences between Australia and Sweden explain differences in illegitimacy and the effects of particular economic, demographic, and social factors. "Sweden and Australia have both reported the annual number of illegitimate births and bridal pregnancies since 1911. These are the longest annual time series available for these two measures. The Australian and Swedish data have never been subjected to statistical analyses which test assumptions about similarities and differences in causes of trends and fluctuations in illegitimacy across these two nations."
A total of 147 pigs were observed from weaning to marketing to see what effect ulceration of the stomach had on the growth rate. Nine pigs showed ill-thrift and had severe gastric ulcers. These animals ate slowly with frequent regurgitation and at post mortem examination showed constriction of the cardia, caused by cicatrisations of the pars oesophagea, with hypertrophy of the caudal part of the oesophagus. Growth rates of these animals were significantly lower than those of normal pigs.
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Three groups of pigs (total 23 pigs) were fed ad libitum from weaning until market weight and these were compared with three groups of pigs (total 26 pigs) fed ad libitum until 12 weeks of age, and then fed on a restricted regimen (twice per day) until marketed. There was a significant difference in degree of ulceration between the two feeding regimens; those pigs fed ad libitum had the most severe gastric ulcers. The pigs fed ad libitum, had significantly less agonistic interactions per minute than did the restricted fed pigs. Growth rates of the pigs from weaning to market weight did not differ significantly in the two regimens, although the average pig on ad libitum feeding consumed 182.9 kg, and the restricted fed pigs ate 148.2 kg per pig.
Granulomatous enteritis was diagnosed in a 4-year-old Standarbred mare suffering from chronic weight loss, depression, dependent oedema but not diarrhoea. There was hypoproteinaemia (hypoalbuminaemia), lymphocytopaenia and neglibible carbohydrate absorption from the small intestine. Pathological changes in almost the entire small intestine included proprial infiltration resulting in partial villous atrophy, and granuloma formation beneath the muscularis which was most severe in the ileum. Slight infiltration occurred in the stomach and the colon. The cells were predominantly lymphocytes and histocytes. No acid-fast organisms were found.
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An outbreak of porcine pleuropneumonia in an intensive piggery in south-eastern Queensland is described. Haemophilus parahaemolyticus was isolated from weaner piglets at post-mortem examination. The disease began in weaners and later occurred in suckling piglets 3 weeks of age. It was associated with poor ventilation, hygiene and overcrowding. Treatment and control measures included intramuscular lincomycin hydrochloride (10 mg/Kg body weight), creep feed medication with oxytetracycline (500 g/tonne) and disinfection and improvement of housing. These appeared to be successful.
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