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Biomedical subjects

W Meyer

Publications and source records attributed to W Meyer.

At least 379 records · Page 21Linked to original sources
PubMed1976

[Studies of enterotoxin production by strains of Staphylococcus aureus of different origins (author's transl)].

376 Staphylococcus aureus strains of clinical and epidemiological origin were tested for their ability to produce the enterotoxins, A, B and C1. For these investigations, microagargel precipitation against specific antisera has been used. Additionally these strains were studied by phagetyping, biochemical typing and for their antibiogram. The strains tested came from human pathological processes, mouth throat swabs of healthy people, persons working in hospitals, outbreaks of food poisoning from cows suffering from mastritis and some from milk samples. Most of the strains isolated from food poisonings were associated with enterotoxin-A-production. Among the group of strains from autopsy material, the enterotoxin-B-producing strains were predominant. The strains from human pathological processes which were found to be enterotoxin producing, were mostly belonging to phage group III. With regard to the antibiogram, the enterotoxin-producing strains were somewhat more resistent than the enterotoxin-negative strains. Correlations between the production of enterotoxin B and methicillin resistance did not become evident in our material. The strains were differentiated, too, as to their classification as var. hominis or var. bovis. With one exception, all enterotoxin-producing strains which could be classified in this way, were belonging to var. hominis. From five enterotoxin-producing strains isolated from cattle, only one strain belonged to var. bovis, the other to var. hominis. Obviously the ability to produce the enterotoxins, A, B and C1 is very rare in the group of var. bovis strains.

Animals↗
PubMed1976

[Hemodynamics, metabolism and function of the perfused pancreas under normal temperature].

The canine pancreas-duodenum has been perfused for 3 h with a membrane oxygenator, a pulsatile pump and a heat exchanger at a temperature of 37 degrees C. Among the criteria used in this study, the insulin output into the venous blood in response to glucose administration, as well as pancreas secretion after secretion stimulation were those found to be the most reliable indicators as to the viability of the pancreas. This is further supported by an average oxygen consumption of 0,77 ml O2/100 g at a constant flow of 80 ml/min and a perfusion pressure of 75 mm Hg. The pressure/flow relationship as for any other perfused organ was a safe indicator as to the viability of the perfused pancreas. The functional viability correlated with our anatomical findings.

Animals↗
PubMed1975

[Angina abdominalis: Clinical findings and therapy (author's transl)].

Angiographic and clinical findings of angina abdominalis are demonstrated by the clinical course of four patients. Two of them suffered from athero-sclerotic stenosis and the remaining two from compression of the coeliac trunc respectively the upper mesenteric artery by fibrotic strings. One patient was treated by an interposition of a saphenous vein graft another one by tissue decompression. Two patients were not operated upon, because one of them had sufficient collateral circulation on angiography, and the other denied an operation, he died one year after diagnosis because of an occlusion of the coeliac trunc and the upper mesenteric artery with following gangrene of the small and large intestine. Danger of complete intestinal necrosis following arterial vessel occlusion as well as reconstructive operative procedures on arterial occlusion should be considered.

Angiography↗
PubMed1975

[Experimental surgery in pancreas/autotransplantation (author's transl)].

We have described to technique of one stage intraabdominal heterotopic pancreaticduodenal autotransplantation which has resulted in long term survival of dogs in good health. Malnutrition related to pancreatic exocrine hypofunction occurs initially but gradual recovery by 3 months nutrition is normal. In contrast, endocrine function is well preserved throughout the postoperative period except for a few days immediately after transplantation. Tolbutamide testing showed a significant prolongation of hypoglycemia as compared to controls although glucose tolerance curves were normal. There was no fibrosis after pancreas-autotransplantation. This experimental model is useful for long term evaluation of heterotopic transplantation of the pancreas. Denervation and lymphatic interruption of the pancreas may cause a transient but not definitive influence on pancreatic endocrine or exocrine function.

Animals↗
PubMed1975

Immunofluorescence of peritoneal phagocytes after infection of mice with L-cell-attenuated Chlamydia psittaci 6BC.

Large amounts of particulate antigen of Chlamydia psittaci 6BC attenuated by growth in L cells were phagocytized by peritoneal mononuclear phagocytes during the 1st h after intraperitoneal inoculation. The phagocytes subsequently destroyed the immunofluorescent (IF) properties of the chlamydial antigens. It is suggested that the early damage of phagocytes by lysosomal enzymes activation induced by chlamydiae contributed to the relatively early disappearance of IF antigens from the peritoneal fluids.

Animals↗
PubMed1975

[Side effects of gold therapy].

461 courses of chrysotherapy, mechanisms of action, effects, side effects and treatment of the latter are reported. With regard to changes of skin and mucous membranes, of peripheral blood count, urine, and liver enzymes the necessity of periodic controls is stressed. Before gold injection uncommon sensations as e.g. itching or "metallic taste" should be ruled out.

Agranulocytosis↗